Browsing Harvard Medical School by Keyword "Biological Data Management"

Now showing items 1-4 of 4

    • Gene and Genome Parameters of Mammalian Liver Circadian Genes (LCGs) 

      Wu, Gang; Zhu, Jiang; He, Fuhong; Wang, Weiwei; Hu, Songnian; Yu, Jun (Public Library of Science, 2012)
      The mammalian circadian system controls various physiology processes and behavior responses by regulating thousands of circadian genes with rhythmic expressions. In this study, we redefined circadian-regulated genes based ...

    • The Human Urine Metabolome 

      Bouatra, Souhaila; Aziat, Farid; Mandal, Rupasri; Guo, An Chi; Wilson, Michael R.; Knox, Craig; Bjorndahl, Trent C.; Krishnamurthy, Ramanarayan; Saleem, Fozia; Liu, Philip; Dame, Zerihun T.; Poelzer, Jenna; Huynh, Jessica; Yallou, Faizath S.; Psychogios, Nick; Dong, Edison; Bogumil, Ralf; Roehring, Cornelia; Wishart, David S. (Public Library of Science, 2013)
      Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-to-obtain in large volumes, largely free from interfering proteins or lipids and chemically complex. However, this chemical ...

    • Multi-Edge Gene Set Networks Reveal Novel Insights into Global Relationships between Biological Themes 

      Parikh, Jignesh R.; Xia, Yu; Marto, Jarrod (Public Library of Science, 2012)
      Curated gene sets from databases such as KEGG Pathway and Gene Ontology are often used to systematically organize lists of genes or proteins derived from high-throughput data. However, the information content inherent to ...

    • A Toolbox for Spatiotemporal Analysis of Voltage-Sensitive Dye Imaging Data in Brain Slices 

      Bourgeois, Elliot B.; Johnson, Brian N.; McCoy, Almedia J.; Trippa, Lorenzo; Cohen, Akiva S.; Marsh, Eric D. (Public Library of Science, 2014)
      Voltage-sensitive dye imaging (VSDI) can simultaneously monitor the spatiotemporal electrical dynamics of thousands of neurons and is often used to identify functional differences in models of neurological disease. While ...