Browsing Harvard Medical School by Keyword "CENP-A"
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Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant
(Springer Netherlands, 2013)The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been ... -
The quantitative architecture of centromeric chromatin
(eLife Sciences Publications, Ltd, 2014)The centromere, responsible for chromosome segregation during mitosis, is epigenetically defined by CENP-A containing chromatin. The amount of centromeric CENP-A has direct implications for both the architecture and ...