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    • Association of IREB2 and CHRNA3 Polymorphisms with Airflow Obstruction in Severe Alpha-1 Antitrypsin Deficiency 

      Wood, Alice M; Barker, Alan F; Brantly, Mark L; Campbell, Edward J; Eden, Edward; McElvaney, Gerard; Rennard, Stephen I; Sandhaus, Robert A; Stocks, James M; Stoller, James K; Strange, Charlie; Turino, Gerard; Stockley, Robert A; Silverman, Edwin Kepner; Demeo, Dawn Lisa; Kim, Woo Jin (BioMed Central, 2012)
      Background: The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have ...