Browsing Harvard Medical School by Keyword "CYLD"

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    • SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination 

      Wu, Xiaomian; Fukushima, Hidefumi; North, Brian J.; Nagaoka, Yoshiyuki; Nagashima, Katsuyuki; Deng, Feng; Okabe, Koji; Inuzuka, Hiroyuki; Wei, Wenyi (Impact Journals LLC, 2014)
      CYLD negatively regulates the NF-κB signaling pathway and osteoclast differentiation largely through antagonizing TNF receptor-associated factor (TRAF)-mediated K63-linkage polyubiquitination in osteoclast precursor cells. ...