Browsing Harvard Medical School by Keyword "Cancer Predisposing Conditions and Syndromes"

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    • Inherited Polymorphisms in Hyaluronan Synthase 1 Predict Risk of Systemic B-Cell Malignancies but Not of Breast Cancer 

      Kuppusamy, Hemalatha; Ogmundsdottir, Helga M.; Baigorri, Eva; Warkentin, Amanda; Steingrimsdottir, Hlif; Haraldsdottir, Vilhelmina; Mant, Michael J.; Mackey, John; Johnston, James B.; Adamia, Sophia; Belch, Andrew R.; Pilarski, Linda M. (Public Library of Science, 2014)
      Genetic variations in the hyaluronan synthase 1 gene (HAS1) influence HAS1 aberrant splicing. HAS1 is aberrantly spliced in malignant cells from multiple myeloma (MM) and Waldenstrom macroglobulinemia (WM), but not in their ...