Now showing items 1-2 of 2

    • Pharmacokinetics of Natural and Engineered Secreted Factors Delivered by Mesenchymal Stromal Cells 

      Elman, Jessica S.; Murray, Ryan M.; Wang, Fangjing; Shen, Keyue; Gao, Shan; Conway, Kevin E.; Yarmush, Martin L.; Tannous, Bakhos A.; Weissleder, Ralph; Parekkadan, Biju (Public Library of Science, 2014)
      Transient cell therapy is an emerging drug class that requires new approaches for pharmacological monitoring during use. Human mesenchymal stem cells (MSCs) are a clinically-tested transient cell therapeutic that naturally ...
    • Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus 

      Rajamuthiah, Rajmohan; Fuchs, Beth Burgwyn; Jayamani, Elamparithi; Kim, Younghoon; Larkins-Ford, Jonah; Conery, Annie; Ausubel, Frederick M.; Mylonakis, Eleftherios (Public Library of Science, 2014)
      Staphylococcus aureus, the leading cause of hospital-acquired infections in the United States, is also pathogenic to the model nematode Caenorhabditis elegans. The C. elegans-S. aureus infection model was previously carried ...