Browsing Harvard Medical School by Keyword "KDM1"
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Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
(eLife Sciences Publications, Ltd, 2013)Here, we describe that lysine-specific demethylase 1 (Lsd1/KDM1a), which demethylates histone H3 on Lys4 or Lys9 (H3K4/K9), is an indispensible epigenetic governor of hematopoietic differentiation. Integrative genomic ...