Now showing items 1-4 of 4

    • Cockayne Syndrome Protein B Interacts with and Is Phosphorylated by c-Abl Tyrosine Kinase 

      Inman, Syed Z.; Indig, Fred E.; Cheng, Wen-Hsing; Saxena, Satya P.; Stevnsner, Tinna; Kufe, Donald William; Bohr, Vilhelm A. (Oxford University Press, 2007)
      The Cockayne Syndrome group B (CSB) protein plays important roles in transcription, transcription-coupled nucleotide excision repair and base excision DNA repair. c-Abl kinase also plays a role in DNA repair as a ...
    • Gene Expression-Based Screening for Inhibitors of PDGFR Signaling 

      Antipova, Alena A.; Stockwell, Brent R.; Golub, Todd R. (BioMed Central, 2008)
      Here we describe a proof-of-concept experiment designed to explore the possibility of using gene expression-based high-throughput screening (GE-HTS) to find inhibitors of a signaling cascade, using platelet derived growth ...
    • Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis 

      Dalli, Jesmond; Norling, Lucy V; Montero-Melendez, Trinidad; Canova, Donata Federici; Lashin, Hazem; Pavlov, Anton M; Sukhorukov, Gleb B; Hinds, Charles J; Perretti, Mauro (Blackwell, 2014)
      Incorporation of locally produced signaling molecules into cell-derived vesicles may serve as an endogenous mediator delivery system. We recently reported that levels alpha-2-macroglobulin (A2MG)-containing microparticles ...
    • Selenoproteins Regulate Macrophage Invasiveness and Extracellular Matrix-related Gene Expression 

      Carlson, Bradley A.; Yoo, Min-Hyuk; Sano, Yasuyo; Sengupta, Aniruddha; Kim, Jin Young; Irons, Robert; Gladyshev, Vadim; Hatfield, Dolph L.; Park, Jin Mo (BioMed Central, 2009)
      Background: Selenium, a micronutrient whose deficiency in diet causes immune dysfunction and inflammatory disorders, is thought to exert its physiological effects mostly in the form of selenium-containing proteins ...