Browsing Harvard Medical School by Keyword "addiction"
Now showing items 1-8 of 8
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Developing and Testing Twelve-Step Facilitation for Adolescents with Substance Use Disorder: Manual Development and Preliminary Outcomes
(Libertas Academica, 2016)Adolescent substance use disorder treatment programs are often based on the 12-step philosophy of Alcoholics Anonymous and/or link adolescents to these free resources. Despite this, no studies have developed and rigorously ... -
Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice
(Nature Publishing Group, 2010)Aim: To investigate the effects of ATPM-ET [(−)-3-N-Ethylaminothiazolo [5,4-b]-N-cyclopropylmethylmorphinan hydrochloride] on physical dependence and behavioral sensitization to morphine in mice. Methods: The pharmacological ... -
The Iowa Gambling Task and the three fallacies of dopamine in gambling disorder
(Frontiers Media S.A., 2013)Gambling disorder sufferers prefer immediately larger rewards despite long term losses on the Iowa Gambling Task (IGT), and these impairments are associated with dopamine dysfunctions. Dopamine is a neurotransmitter linked ... -
Life after prison: Exploring how best to support formerly incarcerated opioid users as they seek employment
(2021-06-25)The United States incarcerates 698 individuals per 100,000 residents – more per capita than any other nation (Wagner & Sawyer, 2020). An estimated 65% of incarcerated people have a substance use disorder (SUD) (NIDA, 2020). ... -
Long-term opioid treatment of chronic nonmalignant pain: unproven efficacy and neglected safety?
(Dove Medical Press, 2013)Background: For the past 30 years, opioids have been used to treat chronic nonmalignant pain. This study tests the following hypotheses: (1) there is no strong evidence-based foundation for the conclusion that long-term ... -
Opioid prescriptions for pain and epidemic of overdose death: can the dramatic reduction in anesthesia mortality serve as an example?
(Dove Medical Press, 2016)The annual number of US deaths from prescription-opioid overdose quadrupled between 1999 and 2010 and in 2010 alone reached 16,651. Deaths from opioid overdose have now surpassed the historic death toll from another ... -
Tanning as a substance abuse
(Taylor & Francis, 2014)While few people would deny the appeal of a day in the sun there are some who seem to take it too far. In recent years the concept of ‘tanning addiction’ has become popular and several studies have supported the notion of ... -
Trace Amine Associated Receptor 1 Modulates Behavioral Effects of Ethanol
(Libertas Academica, 2013)Background: Few treatment options for alcohol use disorders (AUDs) exist and more are critically needed. Here, we assessed whether trace amine associated receptor 1 (TAAR1), a modulator of brain monoamine systems, is ...