Browsing Harvard Medical School by Keyword "biocatalysis"
Now showing items 1-3 of 3
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Diversity of Protein and mRNA Forms of Mammalian Methionine Sulfoxide Reductase B1 Due to Intronization and Protein Processing
(Public Library of Science, 2010)Background: Methionine sulfoxide reductases (Msrs) are repair enzymes that protect proteins from oxidative stress by catalyzing stereospecific reduction of oxidized methionine residues. MsrB1 is a selenocysteine-containing ... -
The Internal Sequence of the Peptide-Substrate Determines Its N-Terminus Trimming by ERAP1
(Public Library of Science, 2008)Background: Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims N-terminally extended antigenic peptide precursors down to mature antigenic peptides for presentation by major histocompatibility complex (MHC) class I ... -
Rational and combinatorial tailoring of bioactive cyclic dipeptides
(Frontiers Media S.A., 2015)Modified cyclic dipeptides represent a diverse family of microbial secondary metabolites. They display a broad variety of biological and pharmacological activities and have long been recognized as privileged structures ...