Browsing Harvard Medical School by Keyword "cancer risk factors"

Now showing items 1-4 of 4

    • canEvolve: A Web Portal for Integrative Oncogenomics 

      Samur, Mehmet Kemal; Yan, Zhenyu; Wang, Xujun; Cao, Qingyi; Munshi, Nikhil C.; Li, Cheng; Shah, Parantu K. (Public Library of Science, 2013)
      Background & objective: Genome-wide profiles of tumors obtained using functional genomics platforms are being deposited to the public repositories at an astronomical scale, as a result of focused efforts by individual ...

    • Impact of Circulating Cholesterol Levels on Growth and Intratumoral Androgen Concentration of Prostate Tumors 

      Mostaghel, Elahe A.; Solomon, Keith R.; Pelton, Kristine; Freeman, Michael R.; Montgomery, R. Bruce (Public Library of Science, 2012)
      Prostate cancer (PCa) is the second most common cancer in men. Androgen deprivation therapy (ADT) leads to tumor involution and reduction of tumor burden. However, tumors eventually reemerge that have overcome the absence ...

    • Limited Awareness and Low Immediate Uptake of Pre-Exposure Prophylaxis among Men Who Have Sex with Men Using an Internet Social Networking Site 

      Krakower, Douglas S.; Mimiaga, Matthew James; Rosenberger, Joshua G.; Novak, David S.; Mitty, Jennifer A.; White, Jaclyn M.; Mayer, Kenneth Hugh (Public Library of Science, 2012)
      Background: In 2010, the iPrEx trial demonstrated that oral antiretroviral pre-exposure prophylaxis (PrEP) reduced the risk of HIV acquisition among high-risk men who have sex with men (MSM). The impact of iPrEx on PrEP ...

    • Recurrent Chromosomal Copy Number Alterations in Sporadic Chordomas 

      Le, Long Phi; Nielsen, Gunnlaugur Petur; Rosenberg, Andrew Eric; Thomas, Dafydd; Batten, Julie M.; Deshpande, Vikram; Schwab, Joseph H; Duan, Zhenfeng; Xavier, Ramnik; Hornicek, Francis John; Iafrate, Anthony John (Public Library of Science, 2011)
      The molecular events in chordoma pathogenesis have not been fully delineated, particularly with respect to copy number changes. Understanding copy number alterations in chordoma may reveal critical disease mechanisms that ...