Browsing Harvard Medical School by Keyword "cardiac function"

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    • Cathepsin K knockout alleviates aging-induced cardiac dysfunction 

      Hua, Yinan; Robinson, Timothy J; Cao, Yongtao; Shi, Guo-Ping; Ren, Jun; Nair, Sreejayan (BlackWell Publishing Ltd, 2014)
      Aging is a major risk factor for cardiovascular disease. It has previously been shown that protein levels of cathepsin K, a lysosomal cysteine protease, are elevated in the failing heart and that genetic ablation of cathepsin ...