Browsing Harvard Medical School by Keyword "caspase-3"
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Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons
(Frontiers Media S.A., 2014)Commonly used anesthetic isoflurane has been reported to promote Alzheimer’s disease (AD) neuropathogenesis by inducing caspase-3 activation. However, the up-stream mechanisms of isoflurane’s effects remain largely to be ... -
Homeobox protein VentX induces p53-independent apoptosis in cancer cells
(Impact Journals LLC, 2016)Identifying novel tumor suppressors holds promise for improving cancer treatment. Our recent studies identified VentX, a homeobox transcriptional factor, as a putative tumor suppressor. Here we demonstrate that VentX exerts ...