Browsing Harvard Medical School by Keyword "computerized simulations"

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    • Analysis Method and Experimental Conditions Affect Computed Circadian Phase from Melatonin Data 

      Klerman, Hadassa; St. Hilaire, Melissa A.; Gronfier, Claude; Santhi, Nayantara; Kronauer, Richard E.; Gooley, Joshua James; Hull, Joseph Thomas; Lockley, Steven Ward; Wang, Wei; Klerman, Elizabeth Beryl (Public Library of Science, 2012)
      Accurate determination of circadian phase is necessary for research and clinical purposes because of the influence of the master circadian pacemaker on multiple physiologic functions. Melatonin is presently the most accurate ...