Browsing Harvard Medical School by Keyword "depression"
Now showing items 1-20 of 38
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A brief review of exercise, bipolar disorder, and mechanistic pathways
(Frontiers Media S.A., 2015)Despite evidence that exercise has been found to be effective in the treatment of depression, it is unclear whether these data can be extrapolated to bipolar disorder. Available evidence for bipolar disorder is scant, with ... -
Childhood Maltreatment, Depression, and Suicidal Ideation: Critical Importance of Parental and Peer Emotional Abuse during Developmental Sensitive Periods in Males and Females
(Frontiers Media S.A., 2015)Background: The adverse childhood experience (ACE) study found that risk for depression increased as a function of number of types of childhood maltreatment, and interpret this as a result of cumulative stress. An alternative ... -
Childhood Trauma and COMT Genotype Interact to Increase Hippocampal Activation in Resilient Individuals
(Frontiers Media S.A., 2016)Both childhood trauma and a functional catechol-O-methyltransferase (COMT) genetic polymorphism have been associated with posttraumatic stress disorder (PTSD) and depression; however, it is still unclear whether the two ... -
Chronic Pain Following Physical and Emotional Trauma: The Station Nightclub Fire
(Frontiers Media S.A., 2014)Objective: The purpose of this study was to evaluate factors associated with chronic pain in survivors of a large fire, including those with and without burn injury. Methods: This study employed a survey-based cross-sectional ... -
Clinical application of brain imaging for the diagnosis of mood disorders: the current state of play
(Nature Publishing Group, 2013)In response to queries about whether brain imaging technology has reached the point where it is useful for making a clinical diagnosis and for helping to guide treatment selection, the American Psychiatric Association (APA) ... -
Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)Background: Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severity but the uniformity of ... -
Depression, Stress and Weight Loss in Individuals with Metabolic Syndrome in SHINE, a DPP Translation Study
(2014)OBJECTIVE To examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary-care based, translation of the Diabetes Prevention Program. DESIGN AND METHODS ... -
Derivation and Validation of a Preoperative Prediction Rule for Delirium After Cardiac Surgery
(Ovid Technologies (Wolters Kluwer Health), 2008)Background— Delirium is a common outcome after cardiac surgery. Delirium prediction rules identify patients at risk for delirium who may benefit from targeted prevention strategies, early identification, and treatment of ... -
Dietary flavonoid intake and risk of incident depression in midlife and older women123
(American Society for Nutrition, 2016)Background: The impact of dietary flavonoid intakes on risk of depression is unclear. Objective: We prospectively examined associations between estimated habitual intakes of dietary flavonoids and depression risk. Design: ... -
Does social support mediate the moderating effect of intrinsic religiosity on the relationship between physical health and depressive symptoms among Jews?
(Springer Nature, 2011)Previous research in the general population suggests that intrinsic religiosity moderates (mitigates) the effect of poor physical health on depression. However, few studies have focused specifically on the Jewish community. ... -
Effect of 2 Psychotherapies on Depression and Disease Activity in Pediatric Crohn's Disease
(Lippincott Williams & Wilkins, 2015)Background: Crohn's disease (CD) is associated with depression. It is unclear if psychosocial interventions offer benefit for depressive symptoms during active CD. In this secondary analysis of a larger study of treating ... -
Effectiveness of the Relaxation Response-Based Group Intervention for Treating Depressed Chinese American Immigrants: A Pilot Study
(MDPI, 2014)Background:: This study examined the feasibility, safety and efficacy of an 8-week Relaxation Response (RR)-based group. Methods:: Twenty-two depressed Chinese American immigrants were recruited. Outcomes measures were ... -
Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder
(Lippincott Williams And Wilkins, 2016)The aim of this study was to evaluate the effects of levomilnacipran extended-release (ER) on depression-related fatigue in adults with major depressive disorder. Post-hoc analyses of five phase III trials were carried ... -
Effects of Mindfulness-Based Cognitive Therapy on Body Awareness in Patients with Chronic Pain and Comorbid Depression
(Frontiers Media S.A., 2016)Body awareness has been proposed as one of the major mechanisms of mindfulness interventions, and it has been shown that chronic pain and depression are associated with decreased levels of body awareness. We investigated ... -
Exploring the risk-factor association between depression and incident stroke: a systematic review and meta-analysis
(Dove Medical Press, 2015)There is growing evidence that depression increases the risk of incident stroke. However, few studies have considered possible residual confounding effects by preexistent cerebrovascular and cardiac diseases. Therefore, ... -
The Food and Drug Administration's Deliberations on Antidepressant Use in Pediatric Patients
(American Academy of Pediatrics (AAP), 2005)On February 2, 2004, the Food and Drug Administration organized a joint meeting of the Neuro-Psychopharmacologic Advisory Committee and Pediatric Subcommittee of the Anti-Infective Drugs Advisory Committee to examine the ... -
The functional impact of subsyndromal depressive symptoms in bipolar disorder: Data from STEP-BD
(Elsevier BV, 2009)Background This report describes baseline characteristics and functional outcomes of subjects who have prospectively observed subsyndromal symptoms after a major depressive episode (MDE). Methods All subjects were ... -
Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems
(Frontiers Media S.A., 2015)Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to ... -
Genome-Wide Association Study of Major Depressive Disorder: New Results, Meta-Analysis, and Lessons Learned
(Nature Publishing Group, 2012)Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed ... -
Getting under the Skin: Report from the International Psoriasis Council Workshop on the Role of Stress in Psoriasis
(Frontiers Media S.A., 2016)Psoriasis is a chronic inflammatory skin condition with significant physical and psychosocial comorbidity. A workshop of leading experts in dermatology and psychology with the purpose of better understanding the current ...