Browsing Harvard Medical School by Keyword "endothelin"
Now showing items 1-2 of 2
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Asymmetric Requirement of Surface Epithelial β-Catenin During the Upper and Lower Jaw Development
(Wiley-Liss, Inc., 2012)Background: Intercellular communication between epithelial and mesenchymal cells is central to mammalian craniofacial development. β-catenin is the gateway of canonical Wnt signaling, one of the major evolutionarily conserved ... -
A Review of Sitaxsentan Sodium in Patients with Pulmonary Arterial Hypertension
(Dove Medical Press, 2007)Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which eventually leads to fatal right heart failure. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, is increased in the pulmonary ...