Browsing Harvard Medical School by Keyword "endothelin A"
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A Review of Sitaxsentan Sodium in Patients with Pulmonary Arterial Hypertension
(Dove Medical Press, 2007)Pulmonary arterial hypertension (PAH) is a life threatening, progressive condition which eventually leads to fatal right heart failure. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, is increased in the pulmonary ...