Browsing Harvard Medical School by Keyword "gadolinium"

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    • Molecular MR Imaging of Liver Fibrosis: A Feasibility Study Using Rat and Mouse Models 

      Polasek, Miloslav; Fuchs, Bryan C.; Uppal, Ritika; Schühle, Daniel T.; Alford, Jamu K.; Loving, Galen S.; Yamada, Suguru; Wei, Lan; Lauwers, Gregory Y.; Guimaraes, Alexander Savio Ramos; Tanabe, Kenneth Kenji; Caravan, Peter D. (Elsevier BV, 2012)
      Background & Aims: Liver biopsy, the current clinical gold standard for fibrosis assessment, is invasive and has sampling errors, and is not optimal for screening, monitoring, or clinical decision-making. Fibrosis is ...

    • Molecular MRI of Collagen to Diagnose and Stage Liver Fibrosis 

      Fuchs, Bryan C.; Wang, Huifang; Yang, Yanfei; Wei, Lan; Polasek, Miloslav; Schühle, Daniel T.; Lauwers, Gregory Y.; Parkar, Ashfaq; Sinskey, Anthony J.; Tanabe, Kenneth Kenji; Caravan, Peter D. (Elsevier BV, 2013)
      Background & Aims The gold standard in assessing liver fibrosis is biopsy despite limitations like invasiveness and sampling error and complications including morbidity and mortality. Therefore, there is a major unmet ...