Browsing Harvard Medical School by Keyword "xenografted tumors"

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    • The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells 

      Gomez-Casal, Roberto; Bhattacharya, Chitralekha; Epperly, Michael W.; Basse, Per H.; Wang, Hong; Wang, Xinhui; Proia, David A.; Greenberger, Joel S.; Socinski, Mark A.; Levina, Vera (MDPI, 2015)
      The molecular chaperone HSP90 is involved in stabilization and function of multiple client proteins, many of which represent important oncogenic drivers in NSCLC. Utilization of HSP90 inhibitors as radiosensitizing agents ...