Now showing items 1805-1824 of 17918

    • Blunted Response to Combination Antiretroviral Therapy in HIV Elite Controllers: An International HIV Controller Collaboration 

      Boufassa, Faroudy; Lechenadec, Jérome; Meyer, Laurence; Costagliola, Dominique; Hunt, Peter W.; Pereyra, Florencia; Deeks, Steve; Pancino, Gianfranco; Taulera, Olivier; Lichterfeld, Mathias; Delobel, Pierre; Saez-Cirion, Asier; Lambotte, Olivier (Public Library of Science, 2014)
      Objective: HIV “elite controllers” (ECs) spontaneously control viral load, but some eventually require combination antiretroviral treatment (cART), due to a loss of viral control or a decline in CD4 T-cell counts. Here we ...
    • BMP Signaling Is Required for Controlling Somatic Stem Cell Self-Renewal in the Drosophila Ovary 

      Kirilly, Daniel; Spana, Eric P.; Perrimon, Norbert; Padgett, Richard W.; Xie, Ting (Elsevier (Cell Press), 2005)
    • BMP signaling modulation attenuates cerebral arteriovenous malformation formation in a vertebrate model 

      Walcott, Brian P (Nature Publishing Group, 2014)
      Cerebral arteriovenous malformations (AVMs) are vascular anomalies that carry a high risk of stroke and death. To test potential AVM therapies, a reverse genetics approach was used to model AVMs in zebrafish. Antisense ...
    • BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway 

      Kamiya, Nobuhiro; Ye, Ling; Kobayashi, Tatsuya; Mochida, Yoshiyuki; Yamauchi, Mitsuo; Kronenberg, Henry M.; Feng, Jian Q.; Mishina, Yuji (Company of Biologists, 2008)
      Bone morphogenetic proteins (BMPs) are known to induce ectopic bone. However, it is largely unknown how BMP signaling in osteoblasts directly regulates endogenous bone. This study investigated the mechanism by which BMP ...
    • BMP signaling stimulates cellular differentiation at multiple steps during cartilage development 

      Kobayashi, Tatsuya; Lyons, Karen M.; McMahon, Andrew P.; Kronenberg, Henry M. (National Academy of Sciences, 2005)
      Bone morphogenetic proteins (BMPs) play important roles at multiple stages of endochondral bone formation. However, the roles of BMP signaling in chondrocytes in vivo are still contentious. In the present study, we ...
    • BMP4 Signaling is Involved in the Generation of Inner Ear Sensory Epithelia 

      Li, Huawei; Corrales, Carleton E; Wang, Zhengmin; Zhao, Yanling; Wang, Yucheng; Heller, Stefan; Liu, Hong (BioMed Central, 2005)
      Background: The robust expression of BMP4 in the incipient sensory organs of the inner ear suggests possible roles for this signaling protein during induction and development of auditory and vestibular sensory epithelia. ...
    • Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth 

      Tomita, Mayumi; Asada, Misako; Asada, Nariaki; Nakamura, Jin; Oguchi, Akiko; Higashi, Atsuko Y.; Endo, Shuichiro; Robertson, Elizabeth; Kimura, Takeshi; Kita, Toru; Economides, Aris N.; Kreidberg, Jordan; Yanagita, Motoko (Public Library of Science, 2013)
      The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension and the progression of renal insufficiency. The molecular ...
    • BMS1 Is Mutated in Aplasia Cutis Congenita 

      Marneros, Alexander G. (Public Library of Science, 2013)
      Aplasia cutis congenita (ACC) manifests with localized skin defects at birth of unknown cause, mostly affecting the scalp vertex. Here, genome-wide linkage analysis and exome sequencing was used to identify the causative ...
    • The BODECOST Index (BCI): a composite index for assessing the impact of COPD in real life 

      Dal Negro, Roberto W.; Celli, Bartolome R. (BioMed Central, 2016)
      Background: Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition which is characterized by a dramatic socio-economic impact. Several indices were extensively investigated in order to asses the mortality ...
    • Body esteem in adolescent hair pullers 

      ALTENBURGER, ERIN M.; TUNG, ESTHER S.; KEUTHEN, NANCY J. (Akadémiai Kiadó, 2014)
      Background and aims: Trichotillomania (TTM) often first presents in adolescence, a developmental period marked by vulnerability in body image. To date, no one has studied the relationship between this disorder and body ...
    • Body expressions of emotion do not trigger fear contagion in autism spectrum disorder 

      Hadjikhani, Nouchine; Joseph, Robert M.; Manoach, Dara S.; Naik, Paulami; Snyder, Josh; Dominick, Kelli; Hoge, Rick; Stock, Jan den; Flusberg, Helen Tager; Gelder, Beatrice de (Oxford University Press, 2009)
      Although there is evidence of emotion perception deficits in autism spectrum disorder (ASD), research on this topic has been mostly confined to perception of emotions in faces. Using behavioral measures and 3T functional ...
    • Body Fat Percentage Should Not Be Confused With Lifestyle Behaviors 

      Kyle, Theodore K.; Stanford, Fatima Cody (Elsevier BV, 2016)
    • Body Mass Index and Decline of Cognitive Function 

      Kim, Sujin; Kim, Yongjoo; Park, Sang Min (Public Library of Science, 2016)
      Background: The association between body mass index (BMI) and cognitive function is a public health issue. This study investigated the relationship between obesity and cognitive impairment which was assessed by the Korean ...
    • Body Mass Index Genetic Risk Score and Endometrial Cancer Risk 

      Prescott, Jennifer; Setiawan, Veronica W.; Wentzensen, Nicolas; Schumacher, Fredrick; Yu, Herbert; Delahanty, Ryan; Bernstein, Leslie; Chanock, Stephen J.; Chen, Chu; Cook, Linda S.; Friedenreich, Christine; Garcia-Closas, Monserrat; Haiman, Christopher A.; Le Marchand, Loic; Liang, Xiaolin; Lissowska, Jolanta; Lu, Lingeng; Magliocco, Anthony M.; Olson, Sara H.; Risch, Harvey A.; Shu, Xiao-Ou; Ursin, Giske; Yang, Hannah P.; Kraft, Peter; De Vivo, Immaculata (Public Library of Science, 2015)
      Genome-wide association studies (GWAS) have identified common variants that predispose individuals to a higher body mass index (BMI), an independent risk factor for endometrial cancer. Composite genotype risk scores (GRS) ...
    • Body Mass Index, Smoking and Hypertensive Disorders during Pregnancy: A Population Based Case-Control Study 

      Gudnadóttir, Thuridur A.; Bateman, Brian T.; Hernádez-Díaz, Sonia; Luque-Fernandez, Miguel Angel; Valdimarsdottir, Unnur; Zoega, Helga (Public Library of Science, 2016)
      While obesity is an indicated risk factor for hypertensive disorders of pregnancy, smoking during pregnancy has been shown to be inversely associated with the development of preeclampsia and gestational hypertension. The ...
    • Body Satisfaction and Body Weight: Gender Differences and Sociodemographic Determinants 

      Austin, Sydney Bryn; Haines, Jess; Veugelers, Paul J (BioMed Central, 2009)
      Background: Given the documented links between body satisfaction, weight-related behaviors, and weight change in adolescents, we sought to examine the prevalence of poor body satisfaction in prepubescent girls and boys and ...
    • Body Satisfaction, Weight Gain, and Binge Eating Among Overweight Adolescent Girls 

      Sonneville, Kendrin Rae; Calzo, Jerel; Horton, Nicholas J.; Haines, Jess; Austin, Sydney Bryn; Field, Alison Ellen (2012)
      Objective: To examine if body satisfaction is associated with body mass index (BMI) change and whether it protects against the development of frequent binge eating among overweight and obese adolescent girls. Methods: We ...
    • Body-Mass Index and Mortality Risk in US Blacks Compared to Whites 

      Jackson, Chandra L.; Wang, Nae-Yuh; Yeh, Hsin-Chieh; Szklo, Moyses; Dray-Spira, Rosemary; Brancati, Frederick L. (2013)
      Objective: To compare body-mass index (BMI)-related mortality risk in US Blacks vs. Whites as the relationship appears to differ across race/ethnicity groups. Design and Methods We pooled cross-sectional surveys of nationally ...
    • Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group 

      Di Saverio, Salomone; Coccolini, Federico; Galati, Marica; Smerieri, Nazareno; Biffl, Walter L; Ansaloni, Luca; Tugnoli, Gregorio; Velmahos, George C; Sartelli, Massimo; Bendinelli, Cino; Fraga, Gustavo Pereira; Kelly, Michael D; Moore, Frederick A; Mandalà, Vincenzo; Mandalà, Stefano; Masetti, Michele; Jovine, Elio; Pinna, Antonio D; Peitzman, Andrew B; Leppaniemi, Ari; Sugarbaker, Paul H; Goor, Harry Van; Moore, Ernest E; Jeekel, Johannes; Catena, Fausto (BioMed Central, 2013)
      Background: In 2013 Guidelines on diagnosis and management of ASBO have been revised and updated by the WSES Working Group on ASBO to develop current evidence-based algorithms and focus indications and safety of conservative ...
    • Bolus Estimation—Rethinking the Effect of Meal Fat Content 

      Laxminarayan, Srinivas; Reifman, Jaques; Edwards, Stephanie S.; Wolpert, Howard; Steil, Garry M. (Mary Ann Liebert, Inc., 2015)
      Abstract Background: Traditionally, insulin bolus calculations for managing postprandial glucose levels in individuals with type 1 diabetes rely solely on the carbohydrate content of a meal. However, recent studies have ...