Browsing HMS Scholarly Articles by Title
Now showing items 2033-2052 of 17917
-
Can Acupuncture Treatment Be Double-Blinded? An Evaluation of Double-Blind Acupuncture Treatment of Postoperative Pain
(Public Library of Science, 2015)Blinding protects against bias but the success of blinding is seldom assessed and reported in clinical trials including studies of acupuncture where blinding represents a major challenge. Recently, needles with the potential ... -
Can apparent resting state connectivity arise from systemic fluctuations?
(Frontiers Media S.A., 2015)It is widely accepted that the fluctuations in resting state blood oxygenation level dependent (BOLD) functional MRI (fMRI) reflect baseline neuronal activation through neurovascular coupling; this data is used to infer ... -
Can biowarfare agents be defeated with light?
(Landes Bioscience, 2013)Biological warfare and bioterrorism is an unpleasant fact of 21st century life. Highly infectious and profoundly virulent diseases may be caused in combat personnel or in civilian populations by the appropriate dissemination ... -
Can enriching emotional intelligence improve medical students’ proactivity and adaptability during OB/GYN clerkships?
(IJME, 2015)Objectives: The purpose of this pilot study was to examine our hypothesis that enriching workplace emotional intelligence through resident coaches could improve third-year medical students’ adaptability and proactivity on ... -
Can Focused Trauma Education Initiatives Reduce Mortality or Improve Resource Utilization in a Low-Resource Setting?
(Springer Nature, 2014)BACKGROUND: Over 90% of injury deaths occur in low-income countries. Evaluating the impact of focused trauma courses in these settings is challenging. We hypothesized that implementation of a focused trauma education ... -
Can Managed Health Care Help Manage Health Care-Associated Infections?
(National Center for Infectious Diseases, 2001)Managed-care organizations have a unique opportunity, still largely unrealized, to collaborate with health-care providers and epidemiologists to prevent health care-associated infections. Several attributes make these ... -
Can Modeling of HIV Treatment Processes Improve Outcomes? Capitalizing on an Operations Research Approach to the Global Pandemic
(BioMed Central, 2008)Background: Mathematical modeling has been applied to a range of policy-level decisions on resource allocation for HIV care and treatment. We describe the application of classic operations research (OR) techniques to address ... -
Can osteoarthritis be treated with light?
(BioMed Central, 2013)Osteoarthritis is becoming more problematic as the population ages. Recent reports suggest that the benefit of anti-inflammatory drugs is unimpressive and the incidence of side effects is worrying. Low-level laser (light) ... -
Can purchasing information be used to predict adherence to cardiovascular medications? An analysis of linked retail pharmacy and insurance claims data
(BMJ Publishing Group, 2016)Objective: The use of retail purchasing data may improve adherence prediction over approaches using healthcare insurance claims alone. Design: Retrospective. Setting and participants A cohort of patients who received ... -
Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations
(BMJ Publishing Group, 2015)Background: The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical diagnostics laboratories across Canada. As clinical ... -
Cancer and liver cirrhosis: implications on prognosis and management
(BMJ Publishing Group, 2016)Liver cirrhosis, the end-stage of every chronic liver disease, is not only the major risk factor for the development of hepatocellular carcinoma but also a limiting factor for anticancer therapy of liver and non-hepatic ... -
Cancer aneuploidies are shaped primarily by effects on tumour fitness
(Springer Science and Business Media LLC, 2023-06-28)Aneuploidies—whole-chromosome or whole-arm imbalances—are the most prevalent alteration in cancer genomes1,2. However, it is still debated whether their prevalence is due to selection or because they are readily generated ... -
Cancer cell profiling by barcoding allows multiplexed protein analysis in fine needle aspirates
(American Association for the Advancement of Science, 2014) -
Cancer Cell-Derived Clusterin Modulates the Phosphatidylinositol 3'-Kinase-Akt Pathway through Attenuation of Insulin-Like Growth Factor 1 during Serum Deprivation
(American Society for Microbiology, 2008)Cancer cells in their respective microenvironments must endure various growth-constraining stresses. Under these conditions, the cancer cell-derived factors are thought to modulate the signaling pathways between cell growth ... -
Cancer in first-degree relatives of people with celiac disease
(Wolters Kluwer Health, 2016)Abstract Background: Celiac disease (CD) has been linked to cancer, especially lymphoproliferative malignancy (LPM). Earlier research has shown that first-degree relatives (FDRs) to individuals with CD are at increased ... -
Cancer Incidence Among Those Initiating Insulin Therapy With Glargine Versus Human NPH Insulin
(American Diabetes Association, 2013)OBJECTIVE To add to the evidence on comparative long-term effects of insulin analog glargine versus human NPH insulin on the risk for cancer. RESEARCH DESIGN AND METHODS We identified cohorts of initiators of glargine and ... -
Cancer Incidence following Expansion of HIV Treatment in Botswana
(Public Library of Science, 2015)Background: The expansion of combination antiretroviral treatment (ART) in southern Africa has dramatically reduced mortality due to AIDS-related infections, but the impact of ART on cancer incidence in the region is ... -
Cancer Mortality in Chinese Chrysotile Asbestos Miners: Exposure-Response Relationships
(Public Library of Science, 2013)Objective: This study was conducted to assess the relationship of mortality from lung cancer and other selected causes to asbestos exposure levels. Methods: A cohort of 1539 male workers from a chrysotile mine in China was ... -
Cancer Nanomedicine: From Targeted Delivery to Combination Therapy
(2015)The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of a variety of diseases, including cancer. The unique properties of nanoparticles, such as large surface-to volume ratio, small size, ... -
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
(Elsevier BV, 2014)Cancer nanotherapeutics are progressing at a steady rate; research and development in the field has experienced an exponential growth since early 2000’s. The path to the commercialization of oncology drugs is long and ...