Browsing HMS Scholarly Articles by Title
Now showing items 2147-2166 of 17920
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A Case of Lower Extremity Venous Thrombosis in the Pediatric Emergency Department
(Ovid Technologies (Wolters Kluwer Health), 2011)Unilateral calf swelling and pain is not a common complaint in the pediatric emergency department. We present a case of a 17-year-old male with no past medical history who presented with left leg swelling and pain while ... -
A Case of Radiation-Induced Multifocal Laryngeal Angiosarcoma Presenting as a Diagnostic Dilemma
(Hindawi Publishing Corporation, 2012)Head and neck sarcomas are relatively rare tumors, with angiosarcomas representing a small subset. Angiosarcoma is a malignant endothelial neoplasm characterized by atypical, multilayered, or solid endothelial proliferation ... -
A case report in cardiovascular magnetic resonance: the contrast agent matters in amyloid
(BioMed Central, 2017)Background: Cardiac amyloidosis is a progressive but underdiagnosed and underappreciated cause of heart failure. In the last few years, cardiovascular magnetic resonance (CMR) has become the gold standard for non invasive ... -
Case Report of a Child after Hematopoietic Cell Transplantation with Acute Aspergillus Tracheobronchitis as a Cause for Respiratory Failure
(Hindawi Publishing Corporation, 2016)Rapid respiratory failure due to invasive mycosis of the airways is an uncommon presentation of Aspergillus infection, even in immunocompromised patients, and very few pediatric cases have been reported. Patients with ... -
Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy
(Elsevier BV, 2016)Tracheobronchial tumors include primary malignant tumors, secondary malignant tumors, and benign tumors. Primary malignant tumors of the trachea are rare, representing only 0.1% to 0.4% of all malignant disease. Squamous ... -
Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting
(Springer Nature, 2014)The TEMPI syndrome was recently described in 2011, and is characterized by the constellation of five hallmarks: Telangiectasias, Erythrocytosis and elevated Erythropoietin, Monoclonal gammopathy, Perinephric fluids ... -
Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma
(BMC, 2016)Background: Molecular profiling has uncovered genetic subtypes of glioblastoma (GBM), including tumors with IDH1 mutations that confer increase survival and improved response to standard-of-care therapies. By mapping the ... -
Case Report: Occupationally Related Recurrent Varicella (Chickenpox) in a Hospital Nurse
(National Institute of Environmental Health Sciences, 2005)Commonly accepted outcomes of varicella-zoster virus (VZV) infections include chickenpox (primary) and shingles (recurrence or latency), as well lifetime immunity against chickenpox. We report the case of a registered nurse ... -
Case Report: Successful Staged Ureteroscopic Treatment of a 5 cm Staghorn Renal Calculus
(Hindawi Publishing Corporation, 2012)It is widely accepted that percutaneous nephrostolithotorny (PCNL) is the standard of choice for the removal of large staghorn renal calculi. Although data exists supporting a stagad ureteroscopic as an alternate treatment ... -
A Case Study of the Reproducibility of Transcriptional Reporter Cell-Based RNAi Screens in Drosophila
(BioMed Central, 2007)Off-target effects have been demonstrated to be a major source of false-positives in RNA interference (RNAi) high-throughput screens. In this study, we re-assess the previously published transcriptional reporter-based ... -
Casein Kinase 1 Proteomics Reveal Prohibitin 2 Function in Molecular Clock
(Public Library of Science, 2012)Throughout the day, clock proteins synchronize changes in animal physiology (e.g., wakefulness and appetite) with external cues (e.g., daylight and food). In vertebrates, both casein kinase 1 delta and epsilon (CK1\(\delta\) ... -
A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction
(National Institute of Environmental Health Sciences, 2006)Background: Long-term exposure to particulate air pollution has been associated with an increased risk of dying from cardiopulmonary and ischemic heart disease, yet few studies have evaluated cardiovascular end points other ... -
Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation
(National Academy of Sciences, 2002)Caspase-3 is a major cell death effector protease in the adult and neonatal nervous system. We found a greater number and higher density of cells in the cortex of caspase-3(-/-) adult mice, consistent with a defect in ... -
Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1
(2014)SUMMARY Caspase-11 is a highly inducible caspase that controls both inflammatory responses and cell death. Caspase-11 controls interleukin 1β (IL-1β) secretion by potentiating caspase-1 activation and induces caspase-1-independent ... -
Caspase-8 Inactivation in T Cells Increases Necroptosis and Suppresses Autoimmunity in \(Bim^{−/−}\) Mice
(The Rockefeller University Press, 2011)Dysregulation of either the extrinsic or intrinsic apoptotic pathway can lead to various diseases including immune disorders and cancer. In addition to its role in the extrinsic apoptotic pathway, caspase-8 plays nonapoptotic ... -
Casting Light from the Shadows: Coping and Defenses Amidst a Pandemic
(Physicians Postgraduate Press, Inc, 2020-06-09) -
Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System
(American Diabetes Association, 2012)We investigated whether overexpression of catalase (CAT) in renal proximal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the offspring of dams with maternal diabetes. Male offspring ... -
Catalyzing a Reproductive Health and Social Justice Movement
(Springer US, 2016)Objectives: The maternal and child health (MCH) community, partnering with women and their families, has the potential to play a critical role in advancing a new multi-sector social movement focused on creating a women’s ... -
Catastrophic NAD+ Depletion in Activated T Lymphocytes Through Nampt Inhibition Reduces Demyelination and Disability in EAE
(Public Library of Science, 2009)Nicotinamide phosphoribosyltransferase (Nampt) inhibitors such as FK866 are potent inhibitors of NAD+ synthesis that show promise for the treatment of different forms of cancer. Based on Nampt upregulation in activated T ... -
Catch me if you can: Leukemia Escape after CD19-Directed T Cell Immunotherapies
(Research Network of Computational and Structural Biotechnology, 2016)Immunotherapy is the revolution in cancer treatment of this last decade. Among multiple approaches able to harness the power of the immune system against cancer, T cell based immunotherapies represent one of the most ...