Browsing HMS Scholarly Articles by Title

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    • Clinical and Polysomnographic Correlates of Subjective Sleepiness in Mild Obstructive Sleep Apnea 

      Omobomi, Olabimpe; Batool-Anwar, Salma; Quan, Stuart (Springer Science and Business Media LLC, 2019-06-19)
      Purpose: The decision to treat mild obstructive sleep apnea (OSA) often hinges on the presence of subjective daytime sleepiness. This study was done to identify clinical and polysomnographic features which correlate with ...

    • Clinical and radiologic features of extraskeletal myxoid chondrosarcoma including initial presentation, local recurrence, and metastases 

      Kapoor, Neena; Shinagare, Atul B.; Jagannathan, Jyothi P.; Shah, Shaan H.; Krajewski, Katherine M.; Hornick, Jason L.; Ramaiya, Nikhil H. (Versita, Warsaw, 2014)
      Background: The aim of the study was to evaluate the clinical and imaging features of extraskeletal myxoid chondrosarcoma (EMC) including initial presentation, recurrence, and metastases. Patients and methods. In this ...

    • Clinical application of brain imaging for the diagnosis of mood disorders: the current state of play 

      Savitz, J B; Rauch, Scott Laurence; Drevets, W C (Nature Publishing Group, 2013)
      In response to queries about whether brain imaging technology has reached the point where it is useful for making a clinical diagnosis and for helping to guide treatment selection, the American Psychiatric Association (APA) ...

    • Clinical Application of Somatosensory Amplification in Psychosomatic Medicine 

      Nakao, Mutsuhiro; Barsky, Arthur Joseph (BioMed Central, 2007)
      Many patients with somatoform disorders are frequently encountered in psychosomatic clinics as well as in primary care clinics. To assess such patients objectively, the concept of somatosensory amplification may be useful. ...

    • Clinical applications of microRNAs 

      Hydbring, Per; Badalian-Very, Gayane (F1000Research, 2013)
      MicroRNAs represent a class of small RNAs derived from polymerase II controlled transcriptional regions. The primary transcript forms one or several bulging double stranded hairpins which are processed by Drosha and Dicer ...

    • Clinical Assessment Incorporating a Personal Genome 

      Ashley, Euan A; Butte, Atul J; Wheeler, Matthew T; Chen, Rong; Klein, Teri E; Dewey, Frederick E; Dudley, Joel T; Ormond, Kelly E; Pavlovic, Aleksandra; Morgan, Alexander A; Pushkarev, Dmitry; Neff, Norma F; Hudgins, Louanne; Gong, Li; Hodges, Laura M; Berlin, Dorit S; Thorn, Caroline F; Sangkuhl, Katrin; Hebert, Joan M; Woon, Mark; Sagreiya, Hersh; Whaley, Ryan; Knowles, Joshua W; Chou, Michael; Thakuria, Joseph V; Rosenbaum, Abraham M; Zaranek, Alexander Wait; Church, George; Greely, Henry T; Quake, Stephen R; Altman, Russ B (Elsevier BV, 2010-05)
      Background The cost of genomic information has fallen steeply, but the clinical translation of genetic risk estimates remains unclear. We aimed to undertake an integrated analysis of a complete human genome in a clinical ...

    • Clinical benefit in recurrent glioblastoma from adjuvant NovoTTF-100A and TCCC after temozolomide and bevacizumab failure: a preliminary observation 

      Wong, Eric T; Lok, Edwin; Swanson, Kenneth D (BlackWell Publishing Ltd, 2015)
      The NovoTTF-100A is a device that emits alternating electric fields and it is approved for the treatment of recurrent glioblastoma. It works by perturbing tumor cells during mitosis as they enter anaphase leading to ...

    • Clinical Bioinformatics: Challenges and Opportunities 

      Bellazzi, Riccardo; Masseroli, Marco; Murphy, Shawn Norman; Shabo, Amnon; Romano, Paolo (BioMed Central, 2012)
      Background: Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop, ...

    • Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial 

      Breithardt, Günter; Baumgartner, Helmut; Berkowitz, Scott D.; Hellkamp, Anne S.; Piccini, Jonathan P.; Stevens, Susanna R.; Lokhnygina, Yuliya; Patel, Manesh R.; Halperin, Jonathan L.; Singer, Daniel E.; Hankey, Graeme J.; Hacke, Werner; Becker, Richard C.; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A. A.; Califf, Robert M. (Oxford University Press, 2014)
      Aims We investigated clinical characteristics and outcomes of patients with significant valvular disease (SVD) in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention ...

    • Clinical Characteristics Associated with Antibiotic Treatment Failure for Tuboovarian Abscesses 

      Farid, Huma; Lau, Trevin C.; Karmon, Anatte E.; Styer, Aaron K. (Hindawi Publishing Corporation, 2016)
      Objective:. Although parenteral antibiotic treatment is a standard approach for tuboovarian abscesses, a significant proportion of patients fail therapy and require interventional radiology (IR) guided drainage. The objective ...

    • Clinical Characteristics of Children with Autism Spectrum Disorder and Co-Occurring Epilepsy 

      Viscidi, Emma W.; Triche, Elizabeth W.; Pescosolido, Matthew F.; McLean, Rebecca L.; Joseph, Robert M.; Spence, Sarah J.; Morrow, Eric M. (Public Library of Science, 2013)
      Objectives: To estimate the prevalence of epilepsy in children with Autism Spectrum Disorder (ASD) and to determine the demographic and clinical characteristics of children with ASD and epilepsy in a large patient population. ...

    • Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features 

      Heath, Michelle; Jaimes, Natalia; Lemos, Bianca; Mostaghimi, Arash; Wang, Linda Jade; Peñas, Pablo F.; Nghiem, Paul (Elsevier BV, 2008)
      Merkel cell carcinoma (MCC) is an aggressive skin cancer with a mortality of 33%. Advanced disease at diagnosis is a poor prognostic factor, suggesting that earlier detection may improve outcome. No systematic analysis has ...

    • Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study 

      Ashizawa, Tetsuo; Figueroa, Karla P; Perlman, Susan L; Gomez, Christopher M; Wilmot, George R; Schmahmann, Jeremy D; Ying, Sarah H; Zesiewicz, Theresa A; Paulson, Henry L; Shakkottai, Vikram G; Bushara, Khalaf O; Kuo, Sheng-Han; Geschwind, Michael D; Xia, Guangbin; Mazzoni, Pietro; Krischer, Jeffrey P; Cuthbertson, David; Holbert, Amy Roberts; Ferguson, John H; Pulst, Stefan M; Subramony, SH (BioMed Central, 2013)
      Background: All spinocerebellar ataxias (SCAs) are rare diseases. SCA1, 2, 3 and 6 are the four most common SCAs, all caused by expanded polyglutamine-coding CAG repeats. Their pathomechanisms are becoming increasingly ...

    • Clinical controversies in endoscopic ultrasound 

      Trindade, Arvind J.; Berzin, Tyler M. (Oxford University Press, 2013)
      The field of diagnostic and therapeutic endoscopic ultrasound (EUS) is growing rapidly. Although EUS has enhanced our ability to diagnose and treat a wide variety of GI conditions, there are many controversial issues ...

    • Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis 

      Arvikar, Sheila L; Collier, Deborah S; Fisher, Mark C; Unizony, Sebastian; Cohen, George L; McHugh, Gail; Kawai, Toshihisa; Strle, Klemen; Steere, Allen C (BioMed Central, 2013)
      Introduction: Prior studies have demonstrated an increased frequency of antibodies to Porphyromonas gingivalis (Pg), a leading agent of periodontal disease, in rheumatoid arthritis (RA) patients. However, these patients ...

    • Clinical Differences between Younger and Older Adults with HIV/AIDS Starting Antiretroviral Therapy in Uganda and Zimbabwe: A Secondary Analysis of the DART Trial 

      Parikh, Sujal M.; Obuku, Ekwaro A.; Walker, Sarah A.; Semeere, Aggrey S.; Auerbach, Brandon J.; Hakim, James G.; Mayanja-Kizza, Harriet; Mugyenyi, Peter N.; Salata, Robert A.; Kityo, Cissy M. (Public Library of Science, 2013)
      Objective: Clinical and immunological data about HIV in older adults from low and middle income countries is scarce. We aimed to describe differences between younger and older adults with HIV starting antiretroviral therapy ...

    • Clinical Effectiveness of Health Visitor Training in Psychologically Informed Approaches for Depression in Postnatal Women: Pragmatic Cluster Randomised Trial in Primary Care 

      Morrell, C Jane; Slade, Pauline; Warner, Rachel; Paley, Graham; Dixon, Simon; Walters, Stephen J; Brugha, Traolach; Barkham, Michael; Parry, Gareth John; Nicholl, Jon (BMJ Publishing Group Ltd., 2009)
      Objective: To evaluate benefits for postnatal women of two psychologically informed interventions by health visitors. Design: Prospective cluster trial randomised by general practice, with 18 month follow-up. Setting: 101 ...

    • Clinical experiences of delayed contrast enhancement with cardiac computed tomography: case series 

      Sidhu, Manavjot S; Ghoshhajra, Brian B; Uthamalingam, Shanmugam; Kilcullen, Niamh; Engel, Leif-Christopher; Medina, Hector M; Venkatesh, Vikram; Vorasettakarnkij, Yongkasem; Hoffmann, Udo; Cury, Ricardo C; Abbara, Suhny; Brady, Thomas J (BioMed Central, 2013)
      Background: Myocardial delayed enhancement (MDE) by gadolinium-enhanced cardiac MRI is well established for myocardial scar assessment in ischemic and non-ischemic heart disease. The role of MDE by cardiac CT (CT-MDE) is ...

    • Clinical features of brain metastasis from salivary gland tumors 

      Venteicher, Andrew S; Walcott, Brian; Sheth, Sameer A.; Snuderl, Matija; Patel, Anoop Premswaroop; Curry, William Thomas; Nahed, Brian Vala (Elsevier BV, 2013)
      Salivary gland tumors comprise a group of 24 tumor subtypes with a wide range of clinical behaviors and propensities for metastasis. Several prognostic factors have been identified that help predict the development of ...

    • Clinical Features of Schwannomatosis: A Retrospective Analysis of 87 Patients 

      Merker, Vanessa; Esparza, S.; Smith, M. J.; Stemmer-Rachamimov, Anat; Plotkin, Scott Randall (Alphamed Press, 2012)
      Background. Schwannomatosis is a recently recognized form of neurofibromatosis characterized by multiple noncutaneous schwannomas, a histologically benign nerve sheath tumor. As more cases are identified, the reported ...