Browsing HMS Scholarly Articles by Title

Now showing items 4184-4203 of 17922

    • Diabetes Disrupts the Response of Retinal Endothelial Cells to the Angiomodulator Lysophosphatidic Acid 

      Aranda, Jorge; Motiejunaite, Ruta; Im, Eunok; Kazlauskas, Andrius (American Diabetes Association, 2012)
      The objectives of this study were to investigate how diabetes mellitus (DM) influences responsiveness of retinal neovessels to lysophosphatidic acid (LPA) and to elucidate the underlying mechanism. To this end, we used an ...

    • Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies 

      Jeon, Christie Y.; Murray, Megan B.; Williams, Brian (Public Library of Science, 2008)
      BackgroundSeveral studies have suggested that diabetes mellitus ( DM) increases the risk of active tuberculosis (TB). The rising prevalence of DM in TB- endemic areas may adversely affect TB control. We conducted a systematic ...

    • Diabetes regulates fructose absorption through thioredoxin-interacting protein 

      Dotimas, James R; Lee, Austin W; Schmider, Angela B; Carroll, Shannon H; Shah, Anu; Bilen, Julide; Elliott, Kayla R; Myers, Ronald B; Soberman, Roy J; Yoshioka, Jun; Lee, Richard T (eLife Sciences Publications, Ltd, 2016)
      Metabolic studies suggest that the absorptive capacity of the small intestine for fructose is limited, though the molecular mechanisms controlling this process remain unknown. Here we demonstrate that thioredoxin-interacting ...

    • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells 

      Furuyama, Kenichiro; Chera, Simona; van Gurp, Léon; Oropeza, Daniel; Ghila, Luiza; Damond, Nicolas; Vethe, Heidrun; Paulo, Joao A.; Joosten, Antoinette M.; Berney, Thierry; Bosco, Domenico; Dorrell, Craig; Grompe, Markus; Ræder, Helge; Roep, Bart O.; Thorel, Fabrizio; Herrera, Pedro L. (Springer Science and Business Media LLC, 2019-02-13)
      Cell identity switches, where terminally-differentiated cells convert into different cell-types when stressed, represent a widespread regenerative strategy in animals, yet they are poorly documented in mammals. In mice, ...

    • Diabetes Risk Perception and Intention to Adopt Healthy Lifestyles Among Primary Care Patients 

      Hivert, Marie-France; Warner, Ana Sofia; Shrader, Peter; Grant, Richard William; Meigs, James Benjamin (American Diabetes Association, 2009)
      OBJECTIVE—To examine perceived risk of developing diabetes in primary care patients. RESEARCH DESIGN AND METHODS—We recruited 150 nondiabetic primary care patients. We made standard clinical measurements, collected fasting ...

    • Diabetes, Obesity, and Hypertension May Enhance Associations between Air Pollution and Markers of Systemic Inflammation 

      Dubowsky, Sara D.; Suh, Helen; Schwartz, Joel David; Coull, Brent Andrew; Gold, Diane R. (National Institute of Environmental Health Sciences, 2006)
      Airborne particulate matter (PM) may lead to increased cardiac risk through an inflammatory pathway. Therefore, we investigated associations between ambient PM and markers of systemic inflammation among repeated measures ...

    • Diabetes-Specific Nutrition Algorithm: A Transcultural Program to Optimize Diabetes and Prediabetes Care 

      Mechanick, Jeffrey I.; Marchetti, Albert E.; Apovian, Caroline; Benchimol, Alexander Koglin; Bisschop, Peter H.; Bolio-Galvis, Alexis; Hegazi, Refaat A.; Jenkins, David; Mendoza, Enrique; Sanz, Miguel Leon; Sheu, Wayne Huey-Herng; Tatti, Patrizio; Tsang, Man-Wo; Hamdy, Osama (Current Science Inc., 2012)
      Type 2 diabetes (T2D) and prediabetes have a major global impact through high disease prevalence, significant downstream pathophysiologic effects, and enormous financial liabilities. To mitigate this disease burden, ...

    • Diabetic Microvascular Complications: Possible Targets for Improved Macrovascular Outcomes 

      D'Elia, John Anthony; Bayliss, George; Roshan, Bijan; Maski, Manish; Gleason, Ray Edward; Weinrauch, Larry Allan (Dove Medical Press, 2010)
      The results of recent outcome trials challenge hypotheses that tight control of both glycohemoglobin and blood pressure diminishes macrovascular events and survival among type 2 diabetic patients. Relevant questions exist ...

    • Diabetic Peripheral Neuropathy as a Predictor of Asymptomatic Myocardial Ischemia in Type 2 Diabetes Mellitus: A Cross-Sectional Study 

      Baltzis, Dimitrios; Roustit, Matthieu; Grammatikopoulou, Maria G.; Katsaboukas, Dimitrios; Athanasiou, Vassileios; Iakovou, Ioannis; Veves, Aristidis; Manes, Christos; Trakatelli, Maria-Christina (Springer Healthcare, 2016)
      Introduction: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. As asymptomatic ...

    • Diagnosing Delirium in Older Hospitalized Adults with Dementia: Adapting the Confusion Assessment Method to International Classification of Diseases, Tenth Revision, Diagnostic Criteria 

      Thomas, Christine; Kreisel, Stefan H.; Oster, Peter; Driessen, Martin; Arolt, Volker; Inouye, Sharon (Wiley-Blackwell, 2012)
      OBJECTIVES: To compare performance characteristics of the Confusion Assessment Method (CAM) algorithm for screening and delirium diagnosis with criteria for delirium from the International Classification of Diseases, Tenth ...

    • Diagnosing Early Onset Dementia and Then What? A Frustrating System of Aftercare Resources 

      Chemali, Zeina N.; Schamber, S; Tarbi, EC; Acar, Diler; Avila-Urizar, M (Dove Medical Press, 2012)
      Recent studies indicate that the prevalence of early onset dementia (EOD) is more common than it was once presumed. As such, and considering the substantial challenges EOD presents to the patient, caregivers, and health ...

    • Diagnosing sepsis is subjective and highly variable: a survey of intensivists using case vignettes 

      Rhee, Chanu; Kadri, Sameer S.; Danner, Robert L.; Suffredini, Anthony F.; Massaro, Anthony F.; Kitch, Barrett T.; Lee, Grace; Klompas, Michael (BioMed Central, 2016)
      Background: Sepsis is the focus of national quality improvement programs and a recent public reporting measure from the Centers for Medicare and Medicaid Services. However, diagnosing sepsis requires interpreting nonspecific ...

    • Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology 

      Ludvigsson, Jonas F; Bai, Julio C; Biagi, Federico; Card, Timothy R; Ciacci, Carolina; Ciclitira, Paul J; Green, Peter H R; Hadjivassiliou, Marios; Holdoway, Anne; van Heel, David A; Kaukinen, Katri; Leffler, Daniel A; Leonard, Jonathan N; Lundin, Knut E A; McGough, Norma; Davidson, Mike; Murray, Joseph A; Swift, Gillian L; Walker, Marjorie M; Zingone, Fabiana; Sanders, David S (BMJ Publishing Group, 2014)
      A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature on diagnosis and management of adult coeliac ...

    • The Diagnosis and Management of Pre-invasive Breast Disease: Flat Epithelial Atypia – Classification, Pathologic Features and Clinical Significance 

      Schnitt, Stuart Jay (BioMed Central, 2003)
      Flat epithelial atypia is a descriptive term that encompasses lesions of the breast terminal duct lobular units in which variably dilated acini are lined by one to several layers of epithelial cells, which are usually ...

    • Diagnosis and management of xerostomia and hyposalivation 

      Villa, Alessandro; Connell, Christopher L; Abati, Silvio (Dove Medical Press, 2015)
      Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is dependent upon a careful and detailed history ...

    • Diagnosis and Treatment Trends in Mucopolysaccharidosis I: Findings from the MPS I Registry 

      D’Aco, Kristin; Underhill, Lisa; Rangachari, Lakshmi; Arn, Pamela; Cox, Gerald Frank; Giugliani, Roberto; Okuyama, Torayuki; Wijburg, Frits; Kaplan, Paige (Springer-Verlag, 2012)
      Our objective was to assess how the diagnosis and treatment of mucopolysaccharidosis I (MPS I) have changed over time. We used data from 891 patients in the MPS I Registry, an international observational database, to analyze ...

    • Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Proposed Modification of the Task Force Criteria 

      Marcus, F. I.; McKenna, William; Sherrill, D.; Basso, C.; Bauce, B.; Bluemke, D. A.; Calkins, H.; Corrado, D.; Cox, M. G. P. J.; Daubert, J. P.; Fontaine, G.; Gear, K.; Hauer, R.; Nava, A.; Picard, Michael Howard; Protonotarios, N.; Saffitz, Jeffrey E; Sanborn, Danita M. Yoerger; Steinberg, J. S.; Tandri, H.; Thiene, G.; Towbin, J. A.; Tsatsopoulou, A.; Wichter, T.; Zareba, W. (Ovid Technologies (Wolters Kluwer Health), 2010)
      Background: In 1994, an International Task Force proposed criteria for the clinical diagnosis of ARVC/D which facilitated recognition and interpretation of the frequently non-specific clinical features of ARVC/D. This ...

    • The Diagnosis of Colorectal Cancer in Patients with Symptoms: Finding a Needle in a Haystack 

      Fletcher, Robert H. (BioMed Central, 2009)
      Patients often see primary care physicians with symptoms that might signal colorectal cancer but are also common in adults without cancer. Physicians and patients must then make a difficult decision about whether and how ...

    • Diagnosis of Influenza from Lower Respiratory Tract Sampling after Negative Upper Respiratory Tract Sampling 

      Bogoch, Isaac; Andrews, Jason Randolph; Zachary, Kimon C.; Hohmann, Elizabeth Louise (Landes Bioscience, 2013)
      In this retrospective cohort study, we demonstrate that PCR-confirmed diagnoses of influenza were made solely by lower respiratory sampling in 6.9% of cases, as traditional upper respiratory tract tests were negative, ...

    • Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria 

      Catassi, Carlo; Elli, Luca; Bonaz, Bruno; Bouma, Gerd; Carroccio, Antonio; Castillejo, Gemma; Cellier, Christophe; Cristofori, Fernanda; de Magistris, Laura; Dolinsek, Jernej; Dieterich, Walburga; Francavilla, Ruggiero; Hadjivassiliou, Marios; Holtmeier, Wolfgang; Körner, Ute; Leffler, Dan A.; Lundin, Knut E. A.; Mazzarella, Giuseppe; Mulder, Chris J.; Pellegrini, Nicoletta; Rostami, Kamran; Sanders, David; Skodje, Gry Irene; Schuppan, Detlef; Ullrich, Reiner; Volta, Umberto; Williams, Marianne; Zevallos, Victor F.; Zopf, Yurdagül; Fasano, Alessio (MDPI, 2015)
      Non-Celiac Gluten Sensitivity (NCGS) is a syndrome characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected by either celiac disease ...