Browsing HMS Scholarly Articles by Title
Now showing items 5093-5112 of 17922
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Effect of the micronutrient iodine in thyroid carcinoma angiogenesis
(Impact Journals LLC, 2016)Iodide is a micronutrient essential for thyroid hormone production. The uptake and metabolism of iodide by thyrocytes is crucial to proper thyroid function. Iodide ions are drawn into the thyroid follicular cell via the ... -
Effect of the Ocular Microenvironment in Regulating Corneal Dendritic Cell Maturation
(American Medical Association (AMA), 2007)Objective To determine whether the ocular anterior segment (aqueous humor and cornea) actively inhibits dendritic cell (DC) maturation. Methods Dendritic cells were injected into syngeneic corneas or conjunctivae, ... -
The Effect of the Oral PKC β Inhibitor Ruboxistaurin on Vision Loss in Two Phase 3 Studies
(Association for Research in Vision and Ophthalmology (ARVO), 2013)Purpose.: To assess the effect of ruboxistaurin (RBX) on vision loss through a prospectively defined combined analysis of two phase 3 trials (MBDL and MBCU). Methods.: Patients in both of these 3-year randomized, ... -
Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection
(American Diabetes Association, 2013)The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2XRs) sense ATP released during cell damage-activation, thus regulating T-cell activation. We aim to define the role of P2XRs during islet allograft ... -
The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading
(Wiley, 2012)To better understand the biomechanical mechanisms underlying the association between hyperkyphosis of the thoracic spine and risk of vertebral fracture and other degenerative spinal pathology, we used a previously validated ... -
Effect of TIM-3 Blockade on the Immunophenotype and Cytokine Profile of Murine Uterine NK Cells
(Public Library of Science, 2015)NK cells are the most abundant lymphocyte population in the feto-maternal interface during gestation. The uterine NK cells (uNK) are transient, have a unique immunophenotype and produce a number of cytokines. These cytokines ... -
The Effect of Tobacco Control Measures during a Period of Rising Cardiovascular Disease Risk in India: A Mathematical Model of Myocardial Infarction and Stroke
(Public Library of Science, 2013)Background: We simulated tobacco control and pharmacological strategies for preventing cardiovascular deaths in India, the country that is expected to experience more cardiovascular deaths than any other over the next ... -
Effect of Topical Azithromycin on Corneal Innate Immune Responses
(Association for Research in Vision and Ophthalmology (ARVO), 2011)Purpose. To determine the effect of azithromycin (AZM) in a murine model of corneal inflammation. Methods. The effect of topical AZM was studied in murine corneal inflammation. Corneal inflammation was induced by ... -
Effect of transcranial direct current stimulation combined with gait and mobility training on functionality in children with cerebral palsy: study protocol for a double-blind randomized controlled clinical trial
(BioMed Central, 2013)Background: The project proposes three innovative intervention techniques (treadmill training, mobility training with virtual reality and transcranial direct current stimulation that can be safely administered to children ... -
Effect of Transcranial Direct-Current Stimulation Combined with Treadmill Training on Balance and Functional Performance in Children with Cerebral Palsy: A Double-Blind Randomized Controlled Trial
(Public Library of Science, 2014)Background: Cerebral palsy refers to permanent, mutable motor development disorders stemming from a primary brain lesion, causing secondary musculoskeletal problems and limitations in activities of daily living. The aim ... -
Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance: a pilot randomized study
(BioMed Central, 2014)Background: Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance, increased risk of type II diabetes, and cardiovascular pathology. Recently, investigators ... -
Effect of Tumor Characteristics and Duplication of the Muscularis Mucosae on the Endoscopic Staging of Superficial Barrett Esophagus-related Neoplasia
(Ovid Technologies (Wolters Kluwer Health), 2009)Endoscopic mucosal resection (EMR) is being advocated as a diagnostic, staging, and therapeutic technique for the management of Barrett esophagus (BE)-related neoplasia. With the emergence of new endoluminal therapy including ... -
Effect of type and amount of dietary carbohydrate on biomarkers of glucose homeostasis and C reactive protein in overweight or obese adults: results from the OmniCarb trial
(BMJ Publishing Group, 2016)Objective: The glycemic index (GI) of dietary carbohydrate is thought to affect glucose homeostasis. Recently, the Effect of Amount and Type of Dietary Carbohydrates on Risk for Cardiovascular Heart Disease and Diabetes ... -
Effect of type of dietary fat and ethanol on antioxidant enzyme mRNA induction in rat liver.
(American Society for Biochemistry and Molecular Biology, 1995)We carried out a study to relate the effect of the type of dietary fat and ethanol on antioxidant enzyme mRNA levels in liver in the intragastric feeding rat model. Different types of dietary fat were administered [saturated ... -
The effect of vibrotactile feedback on postural sway during locomotor activities
(BioMed Central, 2013)Background: Although significant progress has been achieved in developing sensory augmentation methods to improve standing balance, attempts to extend this research to locomotion have been quite limited in scope. The goal ... -
Effect of Vitamin K Supplementation on Insulin Resistance in Older Men and Women
(American Diabetes Association, 2008)Objective: Vitamin K has a potentially beneficial role in insulin resistance, but evidence is limited in humans. We tested the hypothesis that vitamin K supplementation for 36 months will improve insulin resistance in older ... -
The effect of weather on respiratory and cardiovascular deaths in 12 U.S. cities.
(National Institute of Environmental Health Sciences, 2002)We carried out time-series analyses in 12 U.S. cities to estimate both the acute effects and the lagged influence of weather on respiratory and cardiovascular disease (CVD) deaths. We fit generalized additive Poisson ... -
Effect of β2-Adrenergic Receptor Polymorphism on Response to Longacting β2 Agonist in Asthma (LARGE Trial): A Genotype-Stratified, Randomised, Placebo-Controlled, Crossover Trial
(Elsevier BV, 2009-11-21)Background Combined long-acting β2-agonist and inhaled corticosteroid (LABA/ICS) therapy improves outcomes in many asthmatics. Some studies suggest that patients homozygous for arginine at the 16th amino-acid position of ... -
Effect on Blood Pressure of Potassium, Calcium, and Magnesium in Women With Low Habitual Intake
(Ovid Technologies (Wolters Kluwer Health), 1998)In populations, dietary intakes of potassium, calcium, and magnesium each have been inversely associated with blood pressure. However, most clinical trials in normotensive populations have not found that dietary supplements ... -
Effective Connectivity of Depth-Structure–Selective Patches in the Lateral Bank of the Macaque Intraparietal Sulcus
(Public Library of Science, 2015)Extrastriate cortical areas are frequently composed of subpopulations of neurons encoding specific features or stimuli, such as color, disparity, or faces, and patches of neurons encoding similar stimulus properties are ...