Browsing HMS Scholarly Articles by Title
Now showing items 5148-5167 of 17922
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Effects of Air Pollution and Blood Mitochondrial DNA Methylation on Markers of Heart Rate Variability
(Wiley-Blackwell, 2016)Background: The mitochondrion is the primary target of oxidative stress in response to exogenous environments. Mitochondrial DNA (mtDNA) is independent from nuclear DNA and uses separate epigenetic machinery to regulate ... -
Effects of Air Pollution and the Introduction of the London Low Emission Zone on the Prevalence of Respiratory and Allergic Symptoms in Schoolchildren in East London: A Sequential Cross-Sectional Study
(Public Library of Science, 2015)The adverse effects of traffic-related air pollution on children’s respiratory health have been widely reported, but few studies have evaluated the impact of traffic-control policies designed to reduce urban air pollution. ... -
Effects of air pollution on heart rate variability: the VA Normative Aging Study
(National Institue of Environmental Health Sciences, 2004)Reduced heart rate variability (HRV), a marker of poor cardiac autonomic function, has been associated with air pollution, especially fine particulate matter [< 2.5 μm in aerodynamic diameter (PM\(_{2.5}\))]. We examined ... -
Effects of Ambient Coarse, Fine, and Ultrafine Particles and Their Biological Constituents on Systemic Biomarkers: A Controlled Human Exposure Study
(NLM-Export, 2015)Background: Ambient coarse, fine, and ultrafine particles have been associated with mortality and morbidity. Few studies have compared how various particle size fractions affect systemic biomarkers. Objectives: We examined ... -
Effects of amino acids on expression of enterococcal vancomycin resistance
(American Society for Microbiology, 1992)The effects of various amino acids on vancomycin MICs obtained with resistant enterococci was investigated by using broth dilution testing. For both the type A (i.e., possessing transferable resistance to teicoplanin and ... -
Effects of an Antisense Oligonucleotide Inhibitor of C‐Reactive Protein Synthesis on the Endotoxin Challenge Response in Healthy Human Male Volunteers
(Blackwell Publishing Ltd, 2014)Background: C‐reactive protein (CRP) binds to damaged cells, activates the classical complement pathway, is elevated in multiple inflammatory conditions, and provides prognostic information on risk of future atherosclerotic ... -
Effects of an Infant-Focused Relationship-Based Hospital and Home Visiting Intervention on Reducing Symptoms of Postpartum Maternal Depression
(Ovid Technologies (Wolters Kluwer Health), 2014)Relationship-based interventions are an effective means for reducing postpartum depression (PPD), but few cost-effective tools that can be administered efficiently in medical and home settings are available or well-studied. ... -
Effects of an Oxycodone Conjugate Vaccine on Oxycodone Self-Administration and Oxycodone-Induced Brain Gene Expression in Rats
(Public Library of Science, 2014)Prescription opioid abuse is an increasing public health concern in the USA. A vaccine comprising a hapten (OXY) conjugated to the carrier protein keyhole limpet hemocyanin (OXY-KLH) has been shown to attenuate the ... -
Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy
(Elmer Press, 2015)Various clinical trials have assessed how intraoperative anesthetics can affect early recovery, hemodynamics and nociception after supratentorial craniotomy. Whether or not the difference in recovery pattern differs in a ... -
Effects of Arterial Transit Delay on Cerebral Blood Flow Quantification Using Arterial Spin Labeling in an Elderly Cohort
(Wiley, 2017-02)Purpose This study is to investigate whether measurement of arterial transit time (ATT) can improve the accuracy of Arterial Spin Labeling (ASL) cerebral blood flow (CBF) quantification in an elderly cohort due to the ... -
Effects of Atorvastatin on Cerebral Blood Flow in Middle-Aged Adults at Risk for Alzheimer’s Disease: A Pilot Study
(Bentham Science Publishers Ltd., 2012-10)Background/Aims Hypercholesterolemia in midlife increases risk for Alzheimer’s disease (AD) and contributes to cerebrovascular dysregulation - an early finding in preclinical AD pathology. Statins improve vascular reactivity, ... -
Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice
(Nature Publishing Group, 2010)Aim: To investigate the effects of ATPM-ET [(−)-3-N-Ethylaminothiazolo [5,4-b]-N-cyclopropylmethylmorphinan hydrochloride] on physical dependence and behavioral sensitization to morphine in mice. Methods: The pharmacological ... -
The Effects of Caffeinated and Decaffeinated Coffee on Sex Hormone-Binding Globulin and Endogenous Sex Hormone Levels: A Randomized Controlled Trial
(BioMed Central, 2012)Background: Findings from observational studies suggest that sex hormone-binding globulin (SHBG) and endogenous sex hormones may be mediators of the putative relation between coffee consumption and lower risk of type 2 ... -
The Effects of Carbohydrate, Unsaturated Fat, and Protein Intake on Measures of Insulin Sensitivity: Results from the OmniHeart Trial
(American Diabetes Association, 2013)OBJECTIVE Impaired insulin sensitivity increases the risk of cardiovascular disease. Although calorie restriction and weight loss increase insulin sensitivity, the effects of modifying macronutrient composition on insulin ... -
Effects of Charged Particles on Human Tumor Cells
(Frontiers Media S.A., 2016)The use of charged particle therapy in cancer treatment is growing rapidly, in large part because the exquisite dose localization of charged particles allows for higher radiation doses to be given to tumor tissue while ... -
Effects of chymostatin and other proteinase inhibitors on protein breakdown and proteolytic activities in muscle
(Portland Press, 1980)To learn more about the enzymes involved in protein catabolism in skeletal and cardiac muscle and to identify selective inhibitors of this process, we studied the effects of proteinase inhibitors on protein turnover in ... -
Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans
(Public Library of Science, 2008)Variation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population ... -
Effects of Computerized Physician Order Entry on Prescribing Practices
(American Medical Association (AMA), 2000-10-09)Background: Computerized order entry systems have the potential to prevent errors, to improve quality of care, and to reduce costs by providing feedback and suggestions to the physician as each order is entered. This study ... -
Effects of Coptis extract combined with chemotherapeutic agents on ROS production, multidrug resistance, and cell growth in A549 human lung cancer cells
(BioMed Central, 2012)Background: Non–small cell lung cancer is associated with high expression of multidrug resistance (MDR) proteins and low production of reactive oxygen species (ROS). Coptis extract (COP), a Chinese medicinal herb, and its ... -
Effects of Corneal Nerve Density on the Response to Treatment in Dry Eye Disease
(Elsevier BV, 2015)Purpose To evaluate whether levels of corneal subbasal nerve fiber length (SNFL) in dry eye disease (DED) could prognosticate the level of improvement in signs and symptoms after treatment. Design Phase IV, ...