Browsing HMS Scholarly Articles by Title
Now showing items 5418-5437 of 17922
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Embryonic Origin and Remodeling of the Urinary and Digestive Outlets
(Public Library of Science, 2013)Separating digestive and urinary outlets is a critical step during mammalian embryogenesis. However, the natural history of these structures is poorly studied, and little is known about their embryonic origin. Here, we ... -
Embryonic Stem Cell Proliferation Stimulated By Altered Anabolic Metabolism From Glucose Transporter 2-Transported Glucosamine
(Nature Publishing Group, 2016)The hexose transporter, GLUT2 (SLC2A2), which is expressed by mouse embryos, is important for survival before embryonic day 10.5, but its function in embryos is unknown. GLUT2 can transport the amino sugar glucosamine ... -
Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine
(BioMed Central, 2011)Embryonic stem (ES) cells are of great interest as a model system for studying early developmental processes and because of their potential therapeutic applications in regenerative medicine. Obtaining a systematic understanding ... -
EMDomics: a robust and powerful method for the identification of genes differentially expressed between heterogeneous classes
(Oxford University Press, 2015)Motivation: A major goal of biomedical research is to identify molecular features associated with a biological or clinical class of interest. Differential expression analysis has long been used for this purpose; however, ... -
Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains
(American Society for Microbiology, 2013-08-30)Enterococcus faecium, natively a gut commensal organism, emerged as a leading cause of multidrug-resistant hospital-acquired infection in the 1980s. As the living record of its adaptation to changes in habitat, we sequenced ... -
The Emergence of Klebsiella pneumoniae Endogenous Endophthalmitis in the USA: Basic and Clinical Advances
(Springer, 2013)Endogenous endophthalmitis (EE) is a rare but devastating infection that occurs secondary to seeding of the intraocular cavity from an extraocular focus. Recent reports suggest the increasing prevalence and incidence of ... -
Emergence of Stable Functional Networks in Long-Term Human Electroencephalography
(Society for Neuroscience, 2012)Functional connectivity networks have become a central focus in neuroscience because they reveal key higher-dimensional features of normal and abnormal nervous system physiology. Functional networks reflect activity-based ... -
The Emergence of Transcriptional Identity in Somatosensory Neurons
(Springer Science and Business Media LLC, 2020-01-08)Over a dozen morphologically and physiologically distinct primary somatosensory neuron subtypes report salient features of our internal and external environments. How specialized gene expression programs emerge during ... -
Emergency and urgent care capacity in a resource-limited setting: an assessment of health facilities in western Kenya
(BMJ Publishing Group, 2014)Objective: Injuries, trauma and non-communicable diseases are responsible for a rising proportion of death and disability in low-income and middle-income countries. Delivering effective emergency and urgent healthcare for ... -
Emergency care in 59 low- and middle-income countries: a systematic review
(World Health Organization, 2015)Abstract Objective: To conduct a systematic review of emergency care in low- and middle-income countries (LMICs). Methods: We searched PubMed, CINAHL and World Health Organization (WHO) databases for reports describing ... -
Emergency department quality and safety indicators in resource-limited settings: an environmental survey
(Springer Berlin Heidelberg, 2015)Background: As global emergency care grows, practical and effective performance measures are needed to ensure high quality care. Our objective was to systematically catalog and classify metrics that have been used to measure ... -
Emergency department rectal temperatures in over 10 years: A retrospective observational study
(Second Affiliated Hospital of Zhejiang University School of Medicine, 2013)BACKGROUND: Fever in patients can provide an important clue to the etiology of a patient's symptoms. Non-invasive temperature sites (oral, axillary, temporal) may be insensitive due to a variety of factors. This has not ... -
Emergency Department Use and Subsequent Hospitalizations Among Members of a High-Deductible Health Plan
(American Medical Association (AMA), 2007)Context Patients evaluated at emergency departments often present with nonemergency conditions that can be treated in other clinical settings. High-deductible health plans have been promoted as a means of reducing ... -
Emergency department visits for acute asthma by adults who ran out of their inhaled medications
(OceanSide Publications, Inc., 2014)This study was designed to determine the percentage of asthma-related emergency department (ED) visits made by patients who recently ran out of their inhaled short-acting beta-agonists or inhaled corticosteroids and to ... -
Emergency medicine and internal medicine trainees’ smartphone use in clinical settings in the United States
(Korea Health Personnel Licensing Examination Institute, 2015-10-29)Purpose: Smartphone technology offers a multitude of applications (apps) that provide a wide range of functions for healthcare professionals. Medical trainees are early adopters of this technology, but how they use ... -
Emergent Rules for Codon Choice Elucidated by Editing Rare Arginine Codons in Escherichia coli
(National Academy of Sciences, 2016-09-20)The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case ... -
Emerging Concepts: Linking Hypoxic Signaling and Cancer Metabolism
(Nature Publishing Group, 2012) -
Emerging Evidence for MicroRNAs as Regulators of Cancer Stem Cells
(Molecular Diversity Preservation International (MDPI), 2011)Cancer stem cells are defined as a subpopulation of cells within a tumor that are capable of self-renewal and differentiation into the heterogeneous cell lineages that comprise the tumor. Many studies indicate that cancer ... -
The emerging genomics and systems biology research lead to systems genomics studies
(BioMed Central, 2014)Synergistically integrating multi-layer genomic data at systems level not only can lead to deeper insights into the molecular mechanisms related to disease initiation and progression, but also can guide pathway-based ... -
Emerging hemodynamic signatures of the right heart (Third International Right Heart Failure Summit, part 2)
(University of Chicago Press, 2014)Abstract Despite the importance of preserved right ventricular structure and function with respect to outcome across the spectrum of lung, cardiac, and pulmonary vascular diseases, only recently have organized efforts ...