Browsing HMS Scholarly Articles by Title
Now showing items 5781-5800 of 17922
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Evaluation and Correction for Optical Scattering Variations in Laser Speckle Rheology of Biological Fluids
(Public Library of Science, 2013)Biological fluids fulfill key functionalities such as hydrating, protecting, and nourishing cells and tissues in various organ systems. They are capable of these versatile tasks owing to their distinct structural and ... -
Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors
(Springer Science and Business Media LLC, 2020-02-10) -
Evaluation and Treatment of a Ureterosciatic Hernia Causing Hydronephrosis and Renal Colic
(Mary Ann Liebert, Inc., 2015)Abstract An 87-year-old female presented with complaints of intermittent severe right renal colic. CT imaging demonstrated a ureterosciatic hernia and moderate hydronephrosis proximal to the portion of the ureter that was ... -
Evaluation and treatment of hypertensive crises in children
(Dove Medical Press, 2016)Hypertensive crises in children are medical emergencies that must be identified, evaluated, and treated promptly and appropriately to prevent end-organ injury and even death. Treatment in the acute setting typically includes ... -
Evaluation and Treatment of Pharyngitis in Primary Care Practice
(American Medical Association (AMA), 2006-07-10)Background The guidelines from the American College of Physicians and the Infectious Diseases Society of America differ with respect to the use of clinical criteria and microbiologic testing to identify adults with ... -
Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide
(Public Library of Science, 2014)Background: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides ... -
Evaluation of 3D fluoroscopic image generation from a single planar treatment image on patient data with a modified XCAT phantom
(IOP Publishing, 2013)Accurate understanding and modeling of respiration-induced uncertainties is essential in image-guided radiotherapy. Explicit modeling of overall lung motion and interaction among different organs promises to be a useful ... -
Evaluation of a Large-Scale Biomedical Data Annotation Initiative
(BioMed Central, 2009)Background: This study describes a large-scale manual re-annotation of data samples in the Gene Expression Omnibus (GEO), using variables and values derived from the National Cancer Institute thesaurus. A framework is ... -
Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine
(Springer Nature, 2016)Purpose Current standard methods to quantify disc height, namely distortion compensated Roentgen analysis (DCRA), have been mostly utilized in the lumbar and cervical spine and have strict exclusion criteria. Specifically, ... -
Evaluation of a questionnaire to assess selected infectious diseases and their risk factors: Findings of a multicenter study
(Springer Berlin Heidelberg, 2014)Background/objectives The risk to die from an infectious disease in Germany has been continuously decreasing over the last century. Since infections are, however, not only causes of death but risk factors for diseases like ... -
Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood Lymphocytes in Patients in Dhaka, Bangladesh
(Public Library of Science, 2013)Background: Rapid and reliable diagnostic assays for enteric (typhoid and paratyphoid) fever are urgently needed. We report the characterization of novel approach utilizing lymphocyte secretions, for diagnosing patients ... -
Evaluation of a web-based portal to improve resident education by neonatology fellows
(Co-Action Publishing, 2014)Background: Integration of web-based educational tools into medical training has been shown to increase accessibility of resources and optimize teaching. We developed a web-based educational portal (WBEP) to support teaching ... -
Evaluation of actigraphy-measured sleep patterns among children with disabilities and associations with caregivers’ educational attainment: results from a cross-sectional study
(BMJ Publishing Group, 2015)Objectives: To use wrist-actrigrphy to collect objective measures of sleep and to characterise actigraphy-measured sleep patterns among children with disabilities. We also assessed the extent to which, if at all, caregivers’ ... -
Evaluation of an Automated Safety Surveillance System Using Risk Adjusted Sequential Probability Ratio Testing
(BioMed Central, 2011)Background: Automated adverse outcome surveillance tools and methods have potential utility in quality improvement and medical product surveillance activities. Their use for assessing hospital performance on the basis of ... -
Evaluation of an Electricity-free, Culture-based Approach for Detecting Typhoidal Salmonella Bacteremia during Enteric Fever in a High Burden, Resource-limited Setting
(Public Library of Science, 2013)Background: In many rural areas at risk for enteric fever, there are few data on Salmonella enterica serotypes Typhi (S. Typhi) and Paratyphi (S. Paratyphi) incidence, due to limited laboratory capacity for microbiologic ... -
Evaluation of an Online Platform for Multiple Sclerosis Research: Patient Description, Validation of Severity Scale, and Exploration of BMI Effects on Disease Course
(Public Library of Science, 2013)Objectives: To assess the potential of an online platform, PatientsLikeMe.com (PLM), for research in multiple sclerosis (MS). An investigation of the role of body mass index (BMI) on MS disease course was conducted to ... -
Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies
(Public Library of Science, 2010)Background: Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk. We aimed to identify whether these variants may ... -
Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
(MyJove Corporation, 2012)Renal function and continence of urine are critically dependent on the proper function of the urinary bladder, which stores urine at low pressure and expels it with a precisely orchestrated contraction. A number of congenital ... -
Evaluation of Cancer Metabolomics Using ex vivo High Resolution Magic Angle Spinning (HRMAS) Magnetic Resonance Spectroscopy (MRS)
(MDPI, 2016)According to World Health Organization (WHO) estimates, cancer is responsible for more deaths than all coronary heart disease or stroke worldwide, serving as a major public health threat around the world. High resolution ... -
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot”
(Public Library of Science, 2010)We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility. We therefore used a two-stage approach ...