Browsing HMS Scholarly Articles by Title
Now showing items 6222-6241 of 17922
-
Feasibility Study of Early Intervention Provider Confidence Following a Neurobehavioural Intervention for High-Risk Newborns
(Informa UK Limited, 2011-09)Study purpose: Early intervention (EI) can ameliorate neurobehavioural difficulties and parental psychosocial distress. Often, EI service providers are not trained to address the unique needs of the high risk parent–infant ... -
Feasibility study of electrocardiographic and respiratory gated, gadolinium enhanced magnetic resonance angiography of pulmonary veins and the impact of heart rate and rhythm on study quality
(BioMed Central, 2014)Background: We aimed to assess the feasibility of 3 dimensional (3D) respiratory and ECG gated, gadolinium enhanced magnetic resonance angiography (MRA) on a 3 Tesla (3 T) scanner for imaging pulmonary veins (PV) and left ... -
Featural and configural face processing in adults and infants: A behavioral and electrophysiological investigation
(Pion Ltd, 2006)We sought to elucidate the behavioral and electrophysiological correlates of face processing, in adults and infants, by manipulating either the featural or configural information within the face. Two different experiments ... -
Feature issue introduction: biophotonic materials and applications
(Optical Society of America, 2016)Biophotonics can be defined as the interplay of light and biological matter. The percolation of new optical technology into the realm of biology has literally shed new light into the inner workings of biological systems. ... -
Feature Selection and Classification of MAQC-II Breast Cancer and Multiple Myeloma Microarray Gene Expression Data
(Public Library of Science, 2009)Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task of analyzing microarray ... -
Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization
(Public Library of Science, 2016)The development of biomedical interventions to reduce acquisition of HIV-1 infection remains a global priority, however their potential effectiveness is challenged by very high HIV-1 envelope diversity. Two large prophylactic ... -
Fed-Batch Fermentation of GM-CSF-Producing Glycoengineered Pichia pastoris Under Controlled Specific Growth Rate
(BioMed Central, 2010)Background: Yeast expression systems with altered N-glycosylation are now available to produce glycoproteins with homogenous, defined N-glycans. However, data on the behaviour of these strains in high cell density cultivation ... -
A Feed-Forward Circuit of Endogenous PGC-1α and Estrogen Related Receptor α Regulates the Neuronal Electron Transport Chain
(Hindawi Publishing Corporation, 2016)Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a central regulator of cellular and mitochondrial metabolism. Cellular bioenergetics are critically important in “energy-guzzling” neurons, but the ... -
Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development
(Cell Press, 2008)We have developed a nonheuristic genome topography scan (GTS) algorithm to characterize the patterns of genomic alterations in human glioblastoma (GBM), identifying frequent p18^{INK4C} and p16^{INK4A} codeletion. Functional ... -
Female Athlete Triad Awareness Among Multispecialty Physicians
(Springer International Publishing, 2015)Background: The female athlete triad (Triad) is a serious condition with lifelong consequences seen in physically active females. Prior studies assessing Triad knowledge among coaches/athletic trainers reported surprisingly ... -
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
(Nature Publishing Group, 2016)To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected ... -
Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target
(eLife Sciences Publications, Ltd, 2014)To identify new approaches to enhance innate immunity to bacterial pneumonia, we investigated the natural experiment of gender differences in resistance to infections. Female and estrogen-treated male mice show greater ... -
Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study
(BioMed Central, 2014)Background: A child who suffers a fracture or a soft-tissue injury at a young age faces an increased risk of subsequent injuries during childhood. This risk could be related to personal and family characteristics or to ... -
Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry
(BioMed Central, 2014)The purposeful application of fermentation in food and beverage preparation, as a means to provide palatability, nutritional value, preservative, and medicinal properties, is an ancient practice. Fermented foods and beverages ... -
Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo
(Public Library of Science, 2013)Previous studies have shown that the small molecule iron transport inhibitor ferristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation. In this investigation, we show that another ... -
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
(Nature Pub. Group, 2015)Brain iron elevation is implicated in Alzheimer's disease (AD) pathogenesis, but the impact of iron on disease outcomes has not been previously explored in a longitudinal study. Ferritin is the major iron storage protein ... -
Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis
(eLife Sciences Publications, Ltd, 2015)NCOA4 is a selective cargo receptor for the autophagic turnover of ferritin, a process critical for regulation of intracellular iron bioavailability. However, how ferritinophagy flux is controlled and the roles of NCOA4 ... -
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
(American Chemical Society, 2014)Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell death. We found that Fer-1 inhibited cell death in cellular models of Huntington’s disease (HD), periventricular leukomalacia ... -
Fertility and Symptom Relief following Robot-Assisted Laparoscopic Myomectomy
(Hindawi Publishing Corporation, 2015)Objective:. To examine success of robot-assisted laparoscopic myomectomy (RALM) measured by sustained symptom relief and fertility. Methods:. This is a retrospective survey of 426 women who underwent RALM for fibroids, ... -
Fertility preservation in female classic galactosemia patients
(BioMed Central, 2013)Almost every female classic galactosemia patient develops primary ovarian insufficiency (POI) as a diet-independent complication of the disease. This is a major concern for patients and their parents, and physicians are ...