Now showing items 9308-9327 of 17918

    • Is Opium a Real Risk Factor for Esophageal Cancer or Just a Methodological Artifact? Hospital and Neighborhood Controls in Case-Control Studies 

      Shakeri, Ramin; Kamangar, Farin; Nasrollahzadeh, Dariush; Nouraie, Mehdi; Khademi, Hooman; Etemadi, Arash; Islami, Farhad; Marjani, Hajiamin; Fahimi, Saman; Sepehr, Alireza; Rahmati, Atieh; Brennan, Paul; Boffetta, Paolo; Malekzadeh, Reza; Majdzadeh, Reza; Abnet, Christian C.; Dawsey, Sanford M. (Public Library of Science, 2012)
      Background: Control selection is a major challenge in epidemiologic case-control studies. The aim of our study was to evaluate using hospital versus neighborhood control groups in studying risk factors of esophageal squamous ...
    • Is the Association of Airborne Particles with Daily Deaths Confounded by Gaseous Air Pollutants? An Approach to Control by Matching 

      Schwartz, Joel David (National Institute of Environmental Health Sciences, 2004)
      Although particulate air pollution has been associated with increased numbers of daily deaths in dozens of cities around the world, issues still remain about the association. Some have questioned the complex modeling used ...
    • Is the Kaiser Permanente Model Superior in Terms of Clinical Integration?: A Comparative Study of Kaiser Permanente, Northern California and the Danish Healthcare System 

      Strandberg-Larsen, Martin; Schiøtz, Michaela L; Silver, Jeremy D; Frølich, Anne; Andersen, John S; Graetz, Ilana; Bellows, Jim; Krasnik, Allan; Rundall, Thomas; Reed, Mary Elizabeth; Hsu, John (BioMed Central, 2010)
      Background: Integration of medical care across clinicians and settings could enhance the quality of care for patients. To date, there is limited data on the levels of integration in practice. Our objective was to compare ...
    • Is the Relationship between Prenatal Exposure to PCB-153 and Decreased Birth Weight Attributable to Pharmacokinetics? 

      Verner, Marc-André; McDougall, Robin; Glynn, Anders; Andersen, Melvin E.; Clewell, Harvey J.; Longnecker, Matthew P. (National Institute of Environmental Health Sciences, 2013)
      Background: A recent meta-analysis based on data from > 7,000 pregnancies reported an association between prenatal polychlorinated biphenyl (PCB)–153 exposure and reduced birth weight. Gestational weight gain, which is ...
    • Is the way to man's heart (and lung) through the abdomen? 

      Owens, Robert Llewellyn; Harris, Robert Scott; Malhotra, Atul (BioMed Central, 2009)
      Intra-abdominal hypertension is increasingly recognized to be both prevalent and clinically important in medical and surgical intensive care units. Intra-abdominal pressure (IAP) can impact organ function throughout the ...
    • Is There a Role for Treating Inflammation in Moyamoya Disease?: A Review of Histopathology, Genetics, and Signaling Cascades 

      Young, Adam M. H.; Karri, Surya K.; Ogilvy, Christopher S.; Zhao, Ninghui (Frontiers Media S.A., 2013)
      Moyamoya disease is a slowly progressing steno-occlusive condition affecting the cerebrovasculature. Affecting the terminal internal carotid arteries (ICA) and there branches, bilaterally, a resulting in a fine vascular ...
    • Is There Adaptation in the Ozone Mortality Relationship: A Multi-City Case-Crossover Analysis 

      Zanobetti, Antonella; Schwartz, Joel David (BioMed Central, 2008)
      Background: Ozone has been associated with daily mortality, mainly in the summer period. Despite the ample literature on adaptation of inflammatory and pulmonary responses to ozone, and the link, in cohort studies, between ...
    • Is There an Association between Advanced Paternal Age and Endophenotype Deficit Levels in Schizophrenia? 

      Tsuang, Debby; Esterberg, Michelle; Braff, David; Calkins, Monica; Cadenhead, Kristin; Dobie, Dorcas; Freedman, Robert; Green, Michael F.; Greenwood, Tiffany; Gur, Raquel; Gur, Ruben; Horan, William; Lazzeroni, Laura C.; Light, Gregory A.; Millard, Steven P.; Olincy, Ann; Nuechterlein, Keith; Seidman, Larry; Siever, Larry; Silverman, Jeremy; Stone, William; Sprock, Joyce; Sugar, Catherine; Swerdlow, Neal; Tsuang, Ming; Turetsky, Bruce; Radant, Allen (Public Library of Science, 2014)
      The children of older fathers have increased risks of developing schizophrenia spectrum disorders, and among those who develop these disorders, those with older fathers present with more severe clinical symptoms. However, ...
    • Is There an Association between Component Separation and Venous Thromboembolism? Analysis of the NSQIP 

      Kim, Kuylhee; Mella, Juan Rodolfo; Ibrahim, Ahmed M. S.; Koolen, Pieter G. L.; Lin, Samuel J. (Wolters Kluwer Health, 2015)
      Background: Patients undergoing incisional/ventral hernia repair are at risk of developing several postoperative complications particularly venous thromboembolism (VTE), which is a major cause of morbidity and mortality. ...
    • Is There an Association between Traumatic Dental Injury and Social Capital, Binge Drinking and Socioeconomic Indicators among Schoolchildren? 

      de Paiva, Haroldo Neves; Paiva, Paula Cristina Pelli; de Paula Silva, Carlos José; Lamounier, Joel Alves; Ferreira e Ferreira, Efigênia; Ferreira, Raquel Conceição; Kawachi, Ichiro; Zarzar, Patrícia Maria (Public Library of Science, 2015)
      Objectives: Traumatic dental injury is defined as trauma caused by forces on a tooth with variable extent and severity. The aim of the present study was to investigate the prevalence of traumatic dental injury and its ...
    • Ischemic Gastropathic Ulcer Mimics Gastric Cancer 

      Daher, Saleh; Lahav, Ziv; Rmeileh, Ayman Abu; Mizrahi, Meir; Khoury, Tawfik (Hindawi Publishing Corporation, 2016)
      Gastric ulcer due to mesenteric ischemia is a rare clinical finding. As a result, few reports of ischemic gastric ulcers have been reported in the literature. The diagnosis of ischemic gastropathy is seldom considered in ...
    • Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells 

      Courties, Gabriel; Herisson, Fanny; Sager, Hendrik; Heidt, Timo; Ye, Yuxiang; Wei, Ying; Sun, Yuan; Severe, Nicolas; Dutta, Partha; Scharff, Jennifer; Scadden, David; Weissleder, Ralph; Swirski, Filip; Moskowitz, Michael; Nahrendorf, Matthias (American Heart Association, 2015)
      Rationale: The mechanisms leading to an expanded neutrophil and monocyte supply after stroke are incompletely understood. Objective: To test the hypothesis that transient middle cerebral artery occlusion (tMCAO) in mice ...
    • The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes 

      Kilic, Gamze; Alvarez-Mercado, Ana I.; Zarrouki, Bader; Opland, Darren; Liew, Chong Wee; Alonso, Laura C.; Myers, Martin G.; Jonas, Jean-Christophe; Poitout, Vincent; Kulkarni, Rohit N.; Mauvais-Jarvis, Franck (Public Library of Science, 2014)
      The female steroid, 17β-estradiol (E2), is important for pancreatic β-cell function and acts via at least three estrogen receptors (ER), ERα, ERβ, and the G-protein coupled ER (GPER). Using a pancreas-specific ERα knockout ...
    • Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation 

      Papas, Klearchos K.; Bellin, Melena D.; Sutherland, David E. R.; Suszynski, Thomas M.; Kitzmann, Jennifer P.; Avgoustiniatos, Efstathios S.; Gruessner, Angelika C.; Mueller, Kathryn R.; Beilman, Gregory J.; Balamurugan, Appakalai N.; Loganathan, Gopalakrishnan; Colton, Clark K.; Koulmanda, Maria; Weir, Gordon C.; Wilhelm, Josh J.; Qian, Dajun; Niland, Joyce C.; Hering, Bernhard J. (Public Library of Science, 2015)
      Background: Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility ...
    • Islet β cell mass in diabetes and how it relates to function, birth, and death 

      Weir, Gordon C; Bonner-Weir, Susan (Blackwell Publishing Ltd, 2013)
      In type 1 diabetes (T1D) β cell mass is markedly reduced by autoimmunity. Type 2 diabetes (T2D) results from inadequate β cell mass and function that can no longer compensate for insulin resistance. The reduction of β cell ...
    • Islets in Type 2 Diabetes: In Honor of Dr. Robert C. Turner 

      Bonner-Weir, Susan; O'Brien, Timothy D. (American Diabetes Association, 2008)
    • Isoflurane-Induced Apoptosis: A Potential Pathogenic Link Between Delirium and Dementia 

      Xie, Zhongcong; Dong, Y.; Maeda, U.; Moir, Robert D.; Inouye, Sharon; Culley, Deborah Jean; Crosby, Gregory; Tanzi, Rudolph Emile (Oxford University Press (OUP), 2006)
      Background. Dementia and delirium have been postulated to share common pathophysiologic mechanisms; however, identification of these unifying mechanisms has remained elusive. The inhalation anesthetic isoflurane has been ...
    • Isolated cell behavior drives the evolution of antibiotic resistance 

      Artemova, Tatiana; Gerardin, Ylaine; Dudley, Carmel; Vega, Nicole M; Gore, Jeff (John Wiley & Sons, Ltd, 2015)
      Bacterial antibiotic resistance is typically quantified by the minimum inhibitory concentration (MIC), which is defined as the minimal concentration of antibiotic that inhibits bacterial growth starting from a standard ...
    • Isolating Live Cells After High-Throughput, Long-Term, Time-Lapse Microscopy 

      Luro, Scott; Potvin-Trottier, Laurent; Okumus, Burak; Paulsson, Johan (Springer Science and Business Media LLC, 2019-11-25)
      Single-cell genetic screens can be incredibly powerful, but current high-throughput platforms do not track dynamics, and even for non-dynamic properties they struggle to separate mutants of interest from phenotypic outliers ...
    • Isolation and Characterization of Distal Lung Progenitor Cells 

      Driscoll, Barbara; Kikuchi, Alex; Lau, Allison N.; Lee, Jooeun; Reddy, Raghava; Jesudason, Edwin; Kim, Carla; Warburton, David (Humana Press, 2012-04-14)
      The majority of epithelial cells in the distal lung of rodents and humans are quiescent in vivo, yet certain cell populations retain an intrinsic capacity to proliferate and differentiate in response to lung injury or in ...