Browsing HMS Scholarly Articles by Keyword "APP-interacting proteins"
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Synaptotagmins interact with APP and promote Aβ generation
(BioMed Central, 2015)Background: Accumulation of the β-amyloid peptide (Aβ) is a major pathological hallmark of Alzheimer’s disease (AD). Recent studies have shown that synaptic Aβ toxicity may directly impair synaptic function. However, ...