Now showing items 1-3 of 3

    • Association between prehospital vitamin D status and incident acute respiratory failure in critically ill patients: a retrospective cohort study 

      Thickett, David R; Moromizato, Takuhiro; Litonjua, Augusto A; Amrein, Karin; Quraishi, Sadeq A; Lee-Sarwar, Kathleen A; Mogensen, Kris M; Purtle, Steven W; Gibbons, Fiona K; Camargo, Carlos A; Giovannucci, Edward; Christopher, Kenneth B (BMJ Publishing Group, 2015)
      Objective: We hypothesise that low 25-hydroxyvitamin D (25(OH)D) levels before hospitalisation are associated with increased risk of acute respiratory failure. Design: Retrospective cohort study. Setting: Medical and ...
    • Moderate Peep After Tracheal Lipopolysaccharide Instillation Prevents Inflammation and Modifies the Pattern of Brain Neuronal Activation 

      Quilez, María Elisa; Rodríguez-González, Raquel; Turon, Marc; Fernandez-Gonzalo, Sol; Villar, Jesús; Kacmarek, Robert M.; Gómez, Ma Nieves; Oliva, Joan Carles; Blanch, Lluís; López-Aguilar, Josefina (Lippincott Williams & Wilkins, 2015)
      ABSTRACT Background: Ventilatory strategy and specifically positive end-expiratory pressure (PEEP) can modulate the inflammatory response and pulmonary-to-systemic translocation of lipopolysaccharide (LPS). Both inflammation ...
    • Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) 

      Dancer, Rachel C A; Parekh, Dhruv; Lax, Sian; D'Souza, Vijay; Zheng, Shengxing; Bassford, Chris R; Park, Daniel; Bartis, D G; Mahida, Rahul; Turner, Alice M; Sapey, Elizabeth; Wei, Wenbin; Naidu, Babu; Stewart, Paul M; Fraser, William D; Christopher, Kenneth B; Cooper, Mark S; Gao, Fang; Sansom, David M; Martineau, Adrian R; Perkins, Gavin D; Thickett, David R (BMJ Publishing Group, 2015)
      Rationale: Vitamin D deficiency has been implicated as a pathogenic factor in sepsis and intensive therapy unit mortality but has not been assessed as a risk factor for acute respiratory distress syndrome (ARDS). Causality ...