Browsing HMS Scholarly Articles by Keyword "Amyloid precursor protein"
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PuF, An Antimetastatic and Developmental Signaling Protein, Interacts with the Alzheimer’s Amyloid-β Precursor Protein via a Tissue-Specific Proximal Regulatory Element (PRE)
(BioMed Central, 2013)Background: Alzheimer’s disease (AD) is intimately tied to amyloid-β (Aβ) peptide. Extraneuronal brain plaques consisting primarily of Aβ aggregates are a hallmark of AD. Intraneuronal Aβ subunits are strongly implicated ...