Browsing HMS Scholarly Articles by Keyword "Antiangiogenesis Therapy"

Now showing items 1-3 of 3

    • An Active Learning Approach for Rapid Characterization of Endothelial Cells in Human Tumors 

      Padmanabhan, Raghav K.; Somasundar, Vinay H.; Griffith, Sandra D.; Zhu, Jianliang; Samoyedny, Drew; Tan, Kay See; Hu, Jiahao; Liao, Xuejun; Carin, Lawrence; Yoon, Sam S.; Flaherty, Keith T.; DiPaola, Robert S.; Heitjan, Daniel F.; Lal, Priti; Feldman, Michael D.; Roysam, Badrinath; Lee, William M. F. (Public Library of Science, 2014)
      Currently, no available pathological or molecular measures of tumor angiogenesis predict response to antiangiogenic therapies used in clinical practice. Recognizing that tumor endothelial cells (EC) and EC activation and ...

    • Evaluation of New Morphometric Parameters of Neoangiogenesis in Human Colorectal Cancer Using Confocal Laser Endomicroscopy (CLE) and Targeted Panendothelial Markers 

      Ciocâlteu, Adriana; Săftoiu, Adrian; Cârţână, Tatiana; Gruionu, Lucian Gheorghe; Pirici, Daniel; Georgescu, Corneliu Cristian; Georgescu, Claudia-Valentina; Gheonea, Dan Ionuţ; Gruionu, Gabriel (Public Library of Science, 2014)
      The tumor microcirculation is characterized by an abnormal vascular network with dilated, tortuous and saccular vessels. Therefore, imaging the tumor vasculature and determining its morphometric characteristics represent ...

    • Probiotic Yeast Inhibits VEGFR Signaling and Angiogenesis in Intestinal Inflammation 

      Chen, Xinhua; Yang, Guoxun; Song, Joo-Hye; Xu, Huansheng; Li, Dan; Goldsmith, Jeffrey David; Zeng, Huiyan; Parsons-Wingerter, Patricia A.; Reinecker, Hans-Christian; Kelly, Ciaran Patrick (Public Library of Science, 2013)
      Background and Aims Saccharomyces boulardii (Sb) can protect against intestinal injury and tumor formation, but how this probiotic yeast controls protective mucosal host responses is unclear. Angiogenesis is an integral ...