Browsing HMS Scholarly Articles by Keyword "Computer Applications"
Now showing items 1-15 of 15
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Approaches to Recording Drug Allergies in Electronic Health Records: Qualitative Study
(Public Library of Science, 2014)Background: Drug allergy represent an important subset of adverse drug reactions that is worthy of attention because many of these reactions are potentially preventable with use of computerised decision support systems. ... -
Digital Surveillance: A Novel Approach to Monitoring the Illegal Wildlife Trade
(Public Library of Science, 2012)A dearth of information obscures the true scale of the global illegal trade in wildlife. Herein, we introduce an automated web crawling surveillance system developed to monitor reports on illegally traded wildlife. A ... -
Evaluation of an Online Platform for Multiple Sclerosis Research: Patient Description, Validation of Severity Scale, and Exploration of BMI Effects on Disease Course
(Public Library of Science, 2013)Objectives: To assess the potential of an online platform, PatientsLikeMe.com (PLM), for research in multiple sclerosis (MS). An investigation of the role of body mass index (BMI) on MS disease course was conducted to ... -
Factors Influencing Performance of Internet-Based Biosurveillance Systems Used in Epidemic Intelligence for Early Detection of Infectious Diseases Outbreaks
(Public Library of Science, 2014)Background: Internet-based biosurveillance systems have been developed to detect health threats using information available on the Internet, but system performance has not been assessed relative to end-user needs and ... -
Fast Association Tests for Genes with FAST
(Public Library of Science, 2013)Gene-based tests of association can increase the power of a genome-wide association study by aggregating multiple independent effects across a gene or locus into a single stronger signal. Recent gene-based tests have ... -
Identifying Gender-Preferred Communication Styles within Online Cancer Communities: A Retrospective, Longitudinal Analysis
(Public Library of Science, 2012)Background: The goal of this research is to determine if different gender-preferred social styles can be observed within the user interactions at an online cancer community. To achieve this goal, we identify and measure ... -
Increased Gray Matter Diffusion Anisotropy in Patients with Persistent Post-Concussive Symptoms following Mild Traumatic Brain Injury
(Public Library of Science, 2013)A significant percentage of individuals diagnosed with mild traumatic brain injury (mTBI) experience persistent post-concussive symptoms (PPCS). Little is known about the pathology of these symptoms and there is often no ... -
Multi-Edge Gene Set Networks Reveal Novel Insights into Global Relationships between Biological Themes
(Public Library of Science, 2012)Curated gene sets from databases such as KEGG Pathway and Gene Ontology are often used to systematically organize lists of genes or proteins derived from high-throughput data. However, the information content inherent to ... -
A Novel Quantitative Approach for Eliminating Sample-To-Sample Variation Using a Hue Saturation Value Analysis Program
(Public Library of Science, 2014)Objectives: As computing technology and image analysis techniques have advanced, the practice of histology has grown from a purely qualitative method to one that is highly quantified. Current image analysis software is ... -
A Pilot Study of an mHealth Application for Healthcare Workers: Poor Uptake Despite High Reported Acceptability at a Rural South African Community-Based MDR-TB Treatment Program
(Public Library of Science, 2013)Introduction: As the South African province of KwaZulu-Natal addresses a growing multidrug-resistant tuberculosis (MDR-TB) epidemic by shifting care and treatment from trained specialty centers to community hospitals, ... -
The Potential of Accelerating Early Detection of Autism through Content Analysis of YouTube Videos
(Public Library of Science, 2014)Abstract Autism is on the rise, with 1 in 88 children receiving a diagnosis in the United States, yet the process for diagnosis remains cumbersome and time consuming. Research has shown that home videos of children can ... -
Product Diversity and Spectrum of Choice in Hospital ePrescribing Systems in England
(Public Library of Science, 2014)Background: ePrescribing systems have considerable potential for improving healthcare quality and safety. With growing expectations about the benefits of such systems, there is evidence of widespread plans to implement ... -
Supporting Diversity in Science through Social Networking
(Public Library of Science, 2013)In this Community Page, we learn how a scientific community leverages social networking tools to connect a group of dispersed scientific researchers in Ciencia Puerto Rico; this effort fosters innovative research and ... -
Teaching the Blind to Find Their Way by Playing Video Games
(Public Library of Science, 2012)Computer based video games are receiving great interest as a means to learn and acquire new skills. As a novel approach to teaching navigation skills in the blind, we have developed Audio-based Environment Simulator (AbES); ... -
Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates
(Public Library of Science, 2012)The identification of protein kinase targets remains a significant bottleneck for our understanding of signal transduction in normal and diseased cellular states. Kinases recognize their substrates in part through sequence ...