Browsing HMS Scholarly Articles by Keyword "Crohn’s disease"

Now showing items 1-11 of 11

    • The Burden of Inflammatory Bowel Disease: A Patient-Reported Qualitative Analysis and Development of a Conceptual Model 

      Devlen, Jennifer; Beusterien, Kathleen; Yen, Linnette; Ahmed, Awais; Cheifetz, Adam S.; Moss, Alan C (Ovid Technologies (Wolters Kluwer Health), 2014)
      Background The aim of this study was to describe the impacts of inflammatory bowel disease (IBD) from the patients’ perspective, and to inform the development of a conceptual model. Methods Focus groups and ...

    • Characteristics of Inflammatory Bowel Disease Serology in Patients With Indeterminate Colitis 

      Sura, Siddharth P.; Ahmed, Awais; Cheifetz, Adam S.; Moss, Alan C (Ovid Technologies (Wolters Kluwer Health), 2014)
      Goals and Background Inflammatory bowel disease (IBD) serology testing is often used in patients with indeterminate colitis (IC) to help distinguish between ulcerative colitis (UC) and Crohn’s disease (CD). We investigated ...

    • Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease 

      Shaw, Kelly A.; Bertha, Madeline; Hofmekler, Tatyana; Chopra, Pankaj; Vatanen, Tommi; Srivatsa, Abhiram; Prince, Jarod; Kumar, Archana; Sauer, Cary; Zwick, Michael E.; Satten, Glen A.; Kostic, Aleksandar D.; Mulle, Jennifer G.; Xavier, Ramnik J.; Kugathasan, Subra (BioMed Central, 2016)
      Background: Gut microbiome dysbiosis has been demonstrated in subjects with newly diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore longitudinal changes in dysbiosis and ascertain ...

    • Early life environment and natural history of inflammatory bowel diseases 

      Guo, Abra Y; Stevens, Betsy W; Wilson, Robin G; Russell, Caitlin N; Cohen, Melissa A; Sturgeon, Holly C; Thornton, Anna; Giallourakis, Cosmas; Khalili, Hamed; Nguyen, Deanna D; Sauk, Jenny; Yajnik, Vijay; Xavier, Ramnik J; Ananthakrishnan, Ashwin N (BioMed Central, 2014)
      Background: Early life exposures may modify risk of inflammatory bowel diseases (IBD; Crohn’s disease (CD), ulcerative colitis (UC)). However, the relationship between early life exposures and natural history of IBD has ...

    • Identification and Characterization of a Novel Association between Dietary Potassium and Risk of Crohn’s Disease and Ulcerative Colitis 

      Khalili, Hamed; Malik, Sakshi; Ananthakrishnan, Ashwin N.; Garber, John J.; Higuchi, Leslie M.; Joshi, Amit; Peloquin, Joanna; Richter, James M.; Stewart, Kathleen O.; Curhan, Gary C.; Awasthi, Amit; Yajnik, Vijay; Chan, Andrew T. (Frontiers Media S.A., 2016)
      Background: Recent animal studies have identified that dietary salt intake may modify the risk and progression of autoimmune disorders through modulation of the IL-23/TH17 pathway, which is critical in the pathogenesis of ...

    • Improving Case Definition of Crohnʼs Disease and Ulcerative Colitis in Electronic Medical Records Using Natural Language Processing 

      Ananthakrishnan, Ashwin; Cai, Tianxi; Savova, Guergana; Cheng, Su-Chun; Chen, Pei; Guzman, Raul; Gainer, Vivian S.; Murphy, Shawn; Szolovits, Peter; Xia, Zongqi; Shaw, Stanley; Churchill, Susanne; Karlson, Elizabeth; Kohane, Isaac; Plenge, Robert M.; Liao, Katherine (Oxford University Press (OUP), 2013-06)
      Introduction Prior studies identifying patients with inflammatory bowel disease (IBD) utilizing administrative codes have yielded inconsistent results. Our objective was to develop a robust electronic medical record (EMR) ...

    • Mean platelet volume: A controversial marker of disease activity in Crohn’s disease 

      Liu, Song; Ren, Jianan; Han, Gang; Wang, Gefei; Gu, Guosheng; Xia, Qiuyuan; Li, Jieshou (BioMed Central, 2012)
      Background: We investigated and compared the capacity of mean platelet volume (MPV) and other inflammatory markers in detecting Crohn’s disease (CD) activity and differentiating CD patients from healthy controls. Methods: ...

    • Nephrolithiasis in patients with inflammatory bowel disease in the community 

      Cury, Dídia Bismara; Moss, Alan C; Schor, Nestor (Dove Medical Press, 2013)
      Background: Inflammatory bowel disease (IBD) has been associated with renal stone formation. The objective of this study was to determine prospectively the prevalence of nephrolithiasis in a community-based population of ...

    • Psychiatric Co-Morbidity Is Associated With Increased Risk of Surgery in Crohn's Disease 

      Ananthakrishnan, Ashwin N; Gainer, V. S.; Perez, R. G.; Cai, T.; Cheng, S.-C.; Savova, G.; Chen, P.; Szolovits, P.; Xia, Z.; De Jager, P. L.; Shaw, S. Y.; Churchill, S.; Karlson, E. W.; Kohane, I.; Perlis, R. H.; Plenge, R. M.; Murphy, S. N.; Liao, K. P. (Wiley-Blackwell, 2013)
      Introduction Psychiatric co-morbidity, in particular major depression and anxiety is common in patients with Crohn’s disease (CD) and ulcerative colitis (UC). Prior studies examining this may be confounded by the ...

    • Self-management in patients with inflammatory bowel disease: strategies, outcomes, and integration into clinical care 

      Plevinsky, Jill M; Greenley, Rachel N; Fishman, Laurie N (Dove Medical Press, 2016)
      Self-management, including medication adherence, is associated with improved health and outcomes for patients with inflammatory bowel disease. The concept of self-management is complex, but can be divided into those aspects ...

    • Similar Risk of Depression and Anxiety Following Surgery or Hospitalization for Crohn's Disease and Ulcerative Colitis 

      Ananthakrishnan, Ashwin N; Gainer, Vivian S; Cai, Tianxi; Perez, Raul Guzman; Cheng, Su-Chun; Savova, Guergana; Chen, Pei; Szolovits, Peter; Xia, Zongqi; De Jager, Philip L; Shaw, Stanley; Churchill, Susanne; Karlson, Elizabeth W; Kohane, Isaac; Perlis, Roy H; Plenge, Robert M; Murphy, Shawn N; Liao, Katherine P (Springer Nature, 2013)
      Introduction Psychiatric co-morbidity is common in Crohn’s disease (CD) and ulcerative colitis (UC). IBD-related surgery or hospitalizations represent major events in the natural history of disease. Whether there is a ...