Browsing HMS Scholarly Articles by Keyword "Diffusion tensor imaging"
Now showing items 1-11 of 11
-
Applying a free-water correction to diffusion imaging data uncovers stress-related neural pathology in depression
(Elsevier, 2015)Diffusion tensor imaging (DTI) holds promise for developing our understanding of white-matter pathology in major depressive disorder (MDD). Variable findings in DTI-based investigations of MDD, however, have thwarted ... -
Atypical development of white matter microstructure of the corpus callosum in males with autism: a longitudinal investigation
(BioMed Central, 2015)Background: The corpus callosum is the largest white matter structure in the brain, and it is the most consistently reported to be atypical in diffusion tensor imaging studies of autism spectrum disorder. In individuals ... -
Brain white matter integrity and association with age at onset in pediatric obsessive-compulsive disorder
(BioMed Central, 2014)Background: Obsessive-compulsive disorder (OCD) is a common and debilitating neuropsychiatric illness thought to involve abnormal connectivity of widespread brain networks, including frontal-striatal-thalamic circuits. At ... -
Fiber Architecture in Remodeled Myocardium Revealed with a Quantitative Diffusion CMR Tractography Framework and Histological Validation
(BioMed Central, 2012)Background: The study of myofiber reorganization in the remote zone after myocardial infarction has been performed in 2D. Microstructural reorganization in remodeled hearts, however, can only be fully appreciated by ... -
Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction☆
(Elsevier, 2013)While the cerebellum plays a critical role in motor coordination and control no studies have investigated its involvement in idiopathic mobility impairment in community-dwelling elderly. In this study we tested the hypothesis ... -
The nature of white matter abnormalities in blast-related mild traumatic brain injury
(Elsevier, 2015)Blast-related traumatic brain injury (TBI) has been a common injury among returning troops due to the widespread use of improvised explosive devices in the Iraq and Afghanistan Wars. As most of the TBIs sustained are in ... -
Poorer frontolimbic white matter integrity is associated with chronic cannabis use, FAAH genotype, and increased depressive and apathy symptoms in adolescents and young adults
(Elsevier, 2014)Background: The heaviest period of cannabis use coincides with ongoing white matter (WM) maturation. Further, cannabis-related changes may be moderated by FAAH genotype (rs324420). We examined the association between ... -
Probing dynamic myocardial microstructure with cardiac magnetic resonance diffusion tensor imaging
(BioMed Central, 2014)This article is an invited editorial comment on the paper entitled “In vivo cardiovascular magnetic resonance diffusion tensor imaging shows evidence of abnormal myocardial laminar orientations and mobility in hypertrophic ... -
Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography
(Elsevier, 2015)Background: Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema ... -
Voxel-based morphometry (VBM) studies in schizophrenia—can white matter changes be reliably detected with VBM?
(Elsevier BV, 2011)Voxel-Based Morphometry (VBM) is a hypothesis-free, whole-brain, voxel-by-voxel analytic method that attempts to compare imaging data between populations. Schizophrenia studies have utilized this method to localize differences ... -
Worth the wait: effects of age of onset of marijuana use on white matter and impulsivity
(Springer Berlin Heidelberg, 2013)Rationale: Marijuana (MJ) use continues to rise, and as the perceived risk of using MJ approaches an all-time historic low, initiation of MJ use is occurring at even younger ages. As adolescence is a critical period of ...