Now showing items 1-3 of 3

    • Effect of substrate stiffness on early human embryonic stem cell differentiation 

      Eroshenko, Nikolai Alexandrovich; Ramachandran, Rukmani; Yadavalli, Vamsi K; Rao, Rajesh Raghavendran (BioMed Central, 2013)
      Background: The pluripotency and self renewing properties of human embryonic stem cells (hESC) make them a valuable tool in the fields of developmental biology, pharmacology and regenerative medicine. Therefore, there ...
    • Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner 

      Chauhan, Vikash Pal Singh; Stylianopoulos, Triantafyllos; Martin, John D.; Popović, Zoran; Chen, Ou; Kamoun, Walid S.; Bawendi, Moungi G.; Fukumura, Dai; Jain, Rakesh K. (Springer Nature, 2012)
      The blood vessels of cancerous tumours are leaky1–3 and poorly organized4–7. This can increase the interstitial fluid pressure (IFP) inside tumours and reduce blood supply to them, which impairs drug delivery8–9. Anti-angiogenic ...
    • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks 

      Malhotra, Deepali; Fletcher, Anne; Astarita, Jillian Leigh; Lukacs-Kornek, Veronika; Tayalia, Prakriti; Gonzalez, Santiago F.; Elpek, Kutlu G.; Chang, Sook Kyung; Knoblich, Konstantin; Hemler, Martin Edward; Brenner, Michael Barry; Carroll, Michael C.; Mooney, David J.; Turley, Shannon J. (Nature Publishing Group, 2012)
      Lymph node stromal cells (LNSCs) closely regulate immunity and self-tolerance, yet key aspects of their biology remain poorly illuminated. Comparative transcriptomic analyses of murine LNSC subsets revealed expression of ...