Browsing HMS Scholarly Articles by Keyword "actin polymerization"
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Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway
(eLife Sciences Publications, Ltd, 2015)Wiscott Aldrich Syndrome protein (WASP) deficiency results in defects in calcium ion signaling, cytoskeletal regulation, gene transcription and overall T cell activation. The activation of WASP constitutes a key pathway ...