Browsing HMS Scholarly Articles by Keyword "autoimmune diseases"

Now showing items 1-4 of 4

    • The Co-Morbidity Burden of Children and Young Adults with Autism Spectrum Disorders 

      Wattanasin, Nich; Churchill, Susanne; Kohane, Isaac Samuel; McMurry, Andrew; MacFadden, Douglas; Rappaport, Leonard Allan; Kunkel, Louis Martens; Bickel, Jonathan; Spence, Sarah J.; Murphy, Shawn Norman; Weber, Griffin M. (Public Library of Science, 2012)
      Objectives: Use electronic health records Autism Spectrum Disorder (ASD) to assess the comorbidity burden of ASD in children and young adults. Study Design: A retrospective prevalence study was performed using a distributed ...

    • IVIg for apparently autoimmune small-fiber polyneuropathy: first analysis of efficacy and safety 

      Liu, Xiaolei; Treister, Roi; Lang, Magdalena; Oaklander, Anne Louise (SAGE Publications, 2018)
      Objectives: Small-fiber polyneuropathy (SFPN) has various underlying causes, including associations with systemic autoimmune conditions. We have proposed a new cause; small-fiber-targeting autoimmune diseases akin to ...

    • PTPN22.6, a Dominant Negative Isoform of PTPN22 and Potential Biomarker of Rheumatoid Arthritis 

      Chang, Hui-Hsin; Tai, Tzong-Shyuan; Lu, Bing; Iannaccone, Christine; Cernadas, Manuela; Weinblatt, Michael Elliott; Shadick, Nancy Ann; Miaw, Shi-Chuen; Ho, I-Cheng (Public Library of Science, 2012)
      PTPN22 is a tyrosine phosphatase and functions as a damper of TCR signals. A C-to-T single nucleotide polymorphism (SNP) located at position 1858 of human PTPN22 cDNA and converting an arginine (R620) to tryptophan (W620) ...

    • Serological Markers for Inflammatory Bowel Disease in AIDS Patients with Evidence of Microbial Translocation 

      Kamat, Anupa U; Ancuta, Petronela; Blumberg, Richard Steven; Gabuzda, Dana Helga (Public Library of Science, 2010)
      Background: Breakdown of the gut mucosal barrier during chronic HIV infection allows translocation of bacterial products such as lipopolysaccharides (LPS) from the gut into the circulation. Microbial translocation also ...