Browsing HMS Scholarly Articles by Keyword "autophagy/lysosome pathway"
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The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1
(Nature Publishing Group, 2012)Aim: Huntingtin protein (Htt) was a neuropathological hallmark in human Huntington's Disease. The study aimed to investigate whether the macroautophagy regulator, Beclin1, was involved in the degradation of Htt. Methods: ...