Browsing HMS Scholarly Articles by Keyword "cancer metabolism"

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    • Sirtuins, Metabolism, and Cancer 

      Martinez-Pastor, Barbara; Mostoslavsky, Raul (Frontiers Research Foundation, 2012)
      More than a decade ago, sirtuins were discovered as a highly conserved family of NAD+-dependent enzymes that extend lifespan in lower organisms. In mammals, sirtuins are key regulators of stress responses and metabolism, ...

    • Untargeted metabolomics for profiling oncogene-specific metabolic signatures of prostate cancer 

      Priolo, Carmen; Loda, Massimo (Taylor & Francis, 2015)
      Oncogene-associated metabolic signatures in prostate cancer, identified by an integrative analysis of cultured cells and murine and human tumors, suggest that AKT activation results in a glycolytic phenotype whereas MYC ...