Browsing HMS Scholarly Articles by Keyword "cardiac remodelling"

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    • Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis 

      Bian, Zhouyan; Cai, Jun; Shen, Di-fei; Li, Hongliang; Chen, Li; Yan, Ling; Tang, Qizhu (John Wiley & Sons, Ltd, 2009)
      Cellular repressor of E1A-stimulated genes (CREG) is a secreted glycoprotein of 220 amino acids. It has been proposed that CREG acts as a ligand that enhances differentiation and/or reduces cell proliferation. CREG has ...

    • Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway 

      Cai, Jun; Yi, Fang-Fang; Bian, Zhou-Yan; Shen, Di-Fei; Yang, Long; Yan, Ling; Tang, Qi-Zhu; Yang, Xin-Chun; Li, Hongliang (Blackwell Publishing Ltd, 2009)
      Abstract Oxidative stress plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. Because crocetin represses oxidative stress in vitro and in vivo, we have suggested that crocetin ...