Browsing HMS Scholarly Articles by Keyword "cardiovascular diseases"
Now showing items 1-9 of 9
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Biomarkers of Dairy Fatty Acids and Risk of Cardiovascular Disease in the Multi‐Ethnic Study of Atherosclerosis
(Blackwell Publishing Ltd, 2013)Background: Evidence regarding the role of dairy fat intake in cardiovascular disease (CVD) has been mixed and inconclusive. Most earlier studies have used self‐reported measures of dietary intake and focused on relatively ... -
Differences in Heart Rate Variability Associated with Long-Term Exposure to NO2
(National Institute of Environmental Health Sciences, 2008)Background: Heart rate variability (HRV), a measure of cardiac autonomic tone, has been associated with cardiovascular morbidity and mortality. Short-term studies have shown that subjects exposed to higher traffic-associated ... -
The Effect of Particulate Air Pollution on Emergency Admissions for Myocardial Infarction: A Multicity Case-Crossover Analysis
(National Institute of Environmental Health Sciences, 2005)Recently, attention has focused on whether particulate air pollution is a specific trigger of myocardial infarction (MI). The results of several studies of single locations assessing the effects of ambient particular matter ... -
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids
(Lippincott Williams & Wilkins, 2015)Rationale: Evidence suggests that the gut microbiome is involved in the development of cardiovascular disease, with the host–microbe interaction regulating immune and metabolic pathways. However, there was no firm evidence ... -
Impact of Notch Signaling on Inflammatory Responses in Cardiovascular Disorders
(Molecular Diversity Preservation International (MDPI), 2013)Notch signaling is a major pathway in cell fate decisions. Since the first reports showing the major role of Notch in embryonic development, a considerable and still growing literature further highlights its key contributions ... -
Plasma Phospholipid Trans‐Fatty Acids Levels, Cardiovascular Diseases, and Total Mortality: The Cardiovascular Health Study
(Blackwell Publishing Ltd, 2014)Background: While self‐reported trans–fatty acid (TFA) consumption is linked to coronary heart disease (CHD), relationships between objective biomarkers of TFA subtypes (t‐16:1n9, total t‐18:1, and cis/trans‐(c/t‐), t/c‐ ... -
Reductions in Atherogenic Lipids and Major Cardiovascular Events: A Pooled Analysis of 10 ODYSSEY Trials Comparing Alirocumab With Control
(Lippincott Williams & Wilkins, 2016)Background: A continuous relationship between reductions in low-density lipoprotein cholesterol (LDL-C) and major adverse cardiovascular events (MACE) has been observed in statin and ezetimibe outcomes trials down to ... -
Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes and Chronic Obstructive Pulmonary Disease: An Analysis From the Platelet Inhibition and Patient Outcomes (PLATO) Trial
(John Wiley and Sons Inc., 2015)Background: Patients with chronic obstructive pulmonary disease (COPD) experiencing acute coronary syndromes (ACS) are at high risk for clinical events. In the Platelet Inhibition and Patient Outcomes (PLATO) trial, ... -
Vasospasm of Atherosclerotic Coronary Arteries Precipitates Acute Ischemic Myocardial Damage in Myocardial Infarction-Prone Strain of the Watanabe Heritable Hyperlipidemic Rabbits
(Ovid Technologies (Wolters Kluwer Health), 2013)Objective—This study tested the hypothesis that vasospasm can trigger coronary plaque injury and acute ischemic myocardial damage. Approach and Results—Myocardial infarction–prone strain of the Watanabe heritable ...