Browsing HMS Scholarly Articles by Keyword "cerebellum"
Now showing items 1-10 of 10
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Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei
(Proceedings of the National Academy of Sciences, 2001)Microarray technology represents a potentially powerful method for identifying cell type- and regionally restricted genes expressed in the brain. Here we have combined a microarray analysis of differential gene expression ... -
Central Integration of Canal and Otolith Signals is Abnormal in Vestibular Migraine
(Frontiers Media S.A., 2014)Vestibular migraine (VM), a common cause of vestibular symptoms within the general population, is a disabling and poorly understood form of dizziness. We sought to examine the underlying pathophysiology of VM with three ... -
Cerebellar associative sensory learning defects in five mouse autism models
(eLife Sciences Publications, Ltd, 2015)Sensory integration difficulties have been reported in autism, but their underlying brain-circuit mechanisms are underexplored. Using five autism-related mouse models, Shank3+/ΔC, Mecp2R308/Y, Cntnap2−/−, L7-Tsc1 ... -
Comprehensive cellular‐resolution atlas of the adult human brain
(John Wiley and Sons Inc., 2016)ABSTRACT Detailed anatomical understanding of the human brain is essential for unraveling its functional architecture, yet current reference atlases have major limitations such as lack of whole‐brain coverage, relatively ... -
Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System
(Frontiers Media S.A., 2014)Background: Deposition of cortical amyloid beta (Aβ) is a correlate of aging and a risk factor for Alzheimer disease (AD). While several higher order cognitive processes involve functional interactions between cortex and ... -
Differential regulation of neurexin at glutamatergic and GABAergic synapses
(Frontiers Media S.A., 2013)Neurexins (Nrxs) have emerged as potential determinants of synaptic specificity, but little is known about their localization at central synapses. Here we show that Nrxs have a remarkably selective localization at distinct ... -
Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study
(BMJ Publishing Group Ltd., 2011)Objective: To evaluate the association of overall and specific headaches with volume of white matter hyperintensities, brain infarcts, and cognition. Design: Population based, cross sectional study. Setting: Epidemiology ... -
Imaging Studies in Focal Dystonias: A Systems Level Approach to Studying a Systems Level Disorder
(Bentham Science Publishers, 2013)Focal dystonias are dystonias that affect one part of the body, and are sometimes task-specific. Brain imaging and transcranial magnetic stimulation techniques have been valuable in defining the pathophysiology of dystonias ... -
Isolation and Culture of Post-Natal Mouse Cerebellar Granule Neuron Progenitor Cells and Neurons
(Journal of Visualized Experiments, 2009)The cerebellar cortex is a well described structure that provides unique opportunities for studying neuronal properties and development. Of the cerebellar neuronal types (granule cells, Purkinje cells and inhibitory ... -
Volume of cerebellar vermis in monozygotic twins discordant for combat exposure: Lack of relationship to post-traumatic stress disorder
(Elsevier BV, 2006)Several functional neuroimaging studies have implicated the cerebellar vermis in post-traumatic stress disorder (PTSD), but there have been no structural neuroimaging studies of this brain structure in PTSD. We utilized ...