Browsing HMS Scholarly Articles by Keyword "congenital heart disease"

Now showing items 1-4 of 4

    • Galectin‐3 Is Elevated and Associated With Adverse Outcomes in Patients With Single‐Ventricle Fontan Circulation 

      Opotowsky, Alexander R.; Baraona, Fernando; Owumi, Justin; Loukas, Brittani; Singh, Michael N.; Valente, Anne Marie; Wu, Fred; Cheng, Susan; Veldtman, Gruschen; Rimm, Eric B.; Landzberg, Michael J. (John Wiley and Sons Inc., 2016)
      Background: Galectin‐3 may play a role in cardiac and noncardiac fibrosis, and elevated circulating levels of this protein predict adverse outcomes in patients with heart failure who do not have congenital heart disease. ...

    • A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels 

      Waterworth, Dawn; O'Rahilly, Stephen; Hivert, Marie-France; Loos, Ruth J. F.; Tanaka, Toshiko; Timpson, Nicholas John; Semple, Robert K.; Soranzo, Nicole; Song, Kijoung; Rocha, Nuno; Grundberg, Elin; Dupuis, Josée; Langenberg, Claudia; Prokopenko, Inga; Sladek, Robert; Aulchenko, Yurii; Waeber, Gerard; Erdmann, Jeanette; Burnett, Mary-Susan; Sattar, Naveed; Devaney, Joseph; Willenborg, Christina; Hingorani, Aroon; Witteman, Jaquelin C. M.; Vollenweider, Peter; Glaser, Beate; Hengstenberg, Christian; Ferrucci, Luigi; Melzer, David; Stark, Klaus; Deanfield, John; Winogradow, Janina; Grassl, Martina; Hall, Alistair S.; Egan, Josephine M.; Ricketts, Sally L.; König, Inke R.; Reinhard, Wibke; Grundy, Scott; Wichmann, H-Erich; Barter, Phil; Mahley, Robert; Kesaniemi, Y. Antero; Rader, Daniel J.; Reilly, Muredach P.; Stewart, Alexandre F. R.; Van Duijn, Cornelia M.; Schunkert, Heribert; Burling, Keith; Deloukas, Panos; Pastinen, Tomi; Samani, Nilesh J.; McPherson, Ruth; Davey Smith, George; Frayling, Timothy M.; Wareham, Nicholas J.; Mooser, Vincent; Spector, Tim D.; Richards, J. Brent; Florez, Jose Carlos; Perry, John R.B.; Saxena, Richa; Evans, David; Meigs, James Benjamin; Thompson, John R.; Epstein, Stephen E. (Public Library of Science, 2009)
      The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for ...

    • Neonatal Mitral Valve Repair in Biventricular Repair, Single Ventricle Palliation, and Secondary Left Ventricular Recruitment: Indications, Techniques, and Mid-Term Outcomes 

      Myers, Patrick O.; Baird, Christopher W.; del Nido, Pedro J.; Pigula, Frank A.; Lang, Nora; Marx, Gerald R.; Emani, Sitaram M. (Frontiers Media S.A., 2015)
      Objectives: Although mitral valve repair is rarely required in neonates, this population is considered to be at high risk for adverse outcomes. The aim of this study was to review the indications for surgery, mechanisms, ...

    • Treprostinil Increases the Number and Angiogenic Potential of Endothelial Progenitor Cells in Children with Pulmonary Hypertension 

      Smadja, David; Mauge, Laetitia; Gaussem, Pascale; d'Audigier, Clément; Israel-Biet, Dominique; Celermajer, David S.; Bonnet, Damien; Lévy, Marilyne (Springer Netherlands, 2010)
      Background Pulmonary vasodilators in general and prostacyclin therapy in particular, have markedly improved the outcome of patients with pulmonary arterial hypertension (PAH). As endothelial dysfunction is a key feature ...