Browsing HMS Scholarly Articles by Keyword "deacetylation"
Now showing items 1-2 of 2
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Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2
(Impact Journals LLC, 2012)The Skp2 (S-phase kinase associated protein 2) oncoprotein is often highly expressed in various types of human cancers. However, the mechanistic basis of its oncogenic function, as well as the upstream regulatory pathway(s) ... -
O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway
(2016)Tumors utilize aerobic glycolysis to support growth and invasion. However, the molecular mechanisms that link metabolism with invasion are not well understood. The nutrient sensor O-linked-β-N-acetylglucosamine (O-GlcNAc) ...