Browsing HMS Scholarly Articles by Keyword "developmental and pediatric neurology"
Now showing items 1-4 of 4
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AAV-Mediated Gene Delivery in Adult GM1-Gangliosidosis Mice Corrects Lysosomal Storage in CNS and Improves Survival
(Public Library of Science, 2010)Background: GM1-gangliosidosis is a glycosphingolipid (GSL) lysosomal storage disease caused by a genetic deficiency of acid β-galactosidase (βgal), which results in the accumulation of GM1-ganglioside and its asialo-form ... -
Lack of Association between Measles Virus Vaccine and Autism with Enteropathy: A Case-Control Study
(Public Library of Science, 2008)Background: The presence of measles virus (MV) RNA in bowel tissue from children with autism spectrum disorders (ASD) and gastrointestinal (GI) disturbances was reported in 1998. Subsequent investigations found no associations ... -
Primary Role of Functional Ischemia, Quantitative Evidence for the Two-Hit Mechanism, and Phosphodiesterase-5 Inhibitor Therapy in Mouse Muscular Dystrophy
(Public Library of Science, 2007)Background: Duchenne Muscular Dystrophy (DMD) is characterized by increased muscle damage and an abnormal blood flow after muscle contraction: the state of functional ischemia. Until now, however, the cause-effect relationship ... -
Temporal Lobe Cortical Electrical Stimulation during the Encoding and Retrieval Phase Reduces False Memories
(Public Library of Science, 2009)A recent study found that false memories were reduced by 36% when low frequency repetitive transcranial magnetic stimulation (rTMS) was applied to the left anterior temporal lobe after the encoding (study) phase. Here we ...