Browsing HMS Scholarly Articles by Keyword "elite controllers"

Now showing items 1-2 of 2

    • Attenuation of Multiple Nef Functions in HIV-1 Elite Controllers 

      Mwimanzi, Philip; Markle, Tristan J; Martin, Eric; Ogata, Yoko; Kuang, Xiaomei T; Tokunaga, Michiyo; Mahiti, Macdonald; Pereyra, Florencia M.; Miura, Toshiyuki; Walker, Bruce David; Brumme, Zabrina L; Brockman, Mark A; Ueno, Takamasa (BioMed Central, 2013)
      Background: Impaired HIV-1 Gag, Pol, and Env function has been described in elite controllers (EC) who spontaneously suppress plasma viremia to < 50 RNA copies/mL; however, activity of the accessory protein Nef remains ...

    • Lessons to be Learned from Natural Control of HIV – Future Directions, Therapeutic, and Preventive Implications 

      Shasha, David; Walker, Bruce D. (Frontiers Media S.A., 2013)
      Accumulating data generated from persons who naturally control HIV without the need for antiretroviral treatment has led to significant insights into the possible mechanisms of durable control of AIDS virus infection. At ...