Browsing HMS Scholarly Articles by Keyword "vaccine development"
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Increased Breadth and Depth of Cytotoxic T Lymphocytes Responses against HIV-1-B Nef by Inclusion of Epitope Variant Sequences
(Public Library of Science, 2011)Different vaccine approaches cope with HIV-1 diversity, ranging from centralized to variability-encompassing antigens. For all these strategies, a concern remains: how does HIV-1 diversity impact epitope recognition by the ...